Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| adipocyte | 5 studies | 27% ± 4% | |
| cardiac muscle cell | 5 studies | 51% ± 12% | |
| type I pneumocyte | 5 studies | 17% ± 2% | |
| oligodendrocyte | 5 studies | 29% ± 10% | |
| GABAergic neuron | 4 studies | 27% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 99% | 1314.98 | 243 / 245 | 67% | 1.68 | 335 / 502 |
| thymus | 95% | 311.76 | 622 / 653 | 38% | 3.08 | 231 / 605 |
| lung | 93% | 345.87 | 538 / 578 | 29% | 1.17 | 331 / 1155 |
| bladder | 100% | 676.81 | 21 / 21 | 13% | 0.38 | 67 / 504 |
| kidney | 90% | 384.44 | 80 / 89 | 18% | 0.40 | 163 / 901 |
| muscle | 100% | 4963.26 | 803 / 803 | 0% | 0 | 0 / 0 |
| heart | 95% | 1121.73 | 814 / 861 | 0% | 0 | 0 / 0 |
| ovary | 33% | 65.33 | 60 / 180 | 61% | 5.00 | 263 / 430 |
| uterus | 49% | 280.51 | 83 / 170 | 29% | 2.90 | 132 / 459 |
| esophagus | 42% | 97.28 | 607 / 1445 | 33% | 1.20 | 61 / 183 |
| skin | 26% | 170.36 | 475 / 1809 | 49% | 3.10 | 230 / 472 |
| brain | 35% | 118.33 | 937 / 2642 | 29% | 2.39 | 207 / 705 |
| breast | 47% | 128.93 | 216 / 459 | 9% | 0.36 | 100 / 1118 |
| adrenal gland | 32% | 88.27 | 82 / 258 | 24% | 1.22 | 55 / 230 |
| blood vessel | 54% | 137.82 | 717 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 49% | 100.57 | 590 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 35% | 62.34 | 124 / 359 | 12% | 0.32 | 34 / 286 |
| spleen | 31% | 53.83 | 75 / 241 | 0% | 0 | 0 / 0 |
| intestine | 23% | 39.37 | 223 / 966 | 6% | 0.22 | 33 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 18% | 0.92 | 8 / 45 |
| pancreas | 2% | 1.92 | 5 / 328 | 12% | 0.29 | 22 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.08 | 2 / 29 |
| liver | 0% | 0 | 0 / 226 | 5% | 0.24 | 21 / 406 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.03 | 1 / 80 |
| peripheral blood | 1% | 1.65 | 6 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006325 | Biological process | chromatin organization |
| GO_0007601 | Biological process | visual perception |
| GO_2001240 | Biological process | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| GO_0048856 | Biological process | anatomical structure development |
| GO_0006281 | Biological process | DNA repair |
| GO_0048839 | Biological process | inner ear development |
| GO_0030154 | Biological process | cell differentiation |
| GO_0045739 | Biological process | positive regulation of DNA repair |
| GO_0009653 | Biological process | anatomical structure morphogenesis |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | EYA4 |
| Protein name | Eyes absent homolog (EC 3.1.3.48) Eyes absent homolog 4 (EC 3.1.3.48) |
| Synonyms | |
| Description | FUNCTION: Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity). . |
| Accessions | A0A804HL00 ENST00000355167.8 ENST00000706301.1 [O95677-5] O95677 A0A8C8KDW0 A0A804HHY3 ENST00000683325.1 A0A0S2Z3Q2 E7ESD5 ENST00000531901.5 F2Z2Y1 E9PLN6 ENST00000355286.12 [O95677-1] ENST00000684773.1 ENST00000430974.6 ENST00000452339.6 [O95677-5] A0A0S2Z3V9 ENST00000431403.3 [O95677-2] Q96CJ7 ENST00000525849.7 |
