SFRP5 | OmnibusX

Name	Number of supported studies	Average coverage
retinal pigment epithelial cell	3 studies	54% ± 24%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SFRP5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	5846.48	328 / 328	87%	84.39	154 / 178
intestine	90%	2163.83	865 / 966	21%	4.59	110 / 527
stomach	69%	713.38	247 / 359	34%	4.57	98 / 286
liver	59%	337.93	134 / 226	37%	49.53	150 / 406
prostate	60%	538.86	146 / 245	30%	1.49	152 / 502
esophagus	64%	987.26	924 / 1445	21%	2.16	39 / 183
adrenal gland	28%	252.59	73 / 258	54%	71.58	125 / 230
lung	13%	77.80	78 / 578	43%	3.37	497 / 1155
ovary	4%	18.20	8 / 180	51%	5.71	219 / 430
heart	52%	2553.04	449 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	46%	3.70	37 / 80
skin	19%	86.21	352 / 1809	26%	5.85	123 / 472
bladder	33%	190.05	7 / 21	12%	0.59	61 / 504
brain	13%	103.65	340 / 2642	32%	4.10	226 / 705
uterus	14%	101.25	24 / 170	19%	2.41	86 / 459
breast	21%	176.86	95 / 459	9%	0.53	96 / 1118
blood vessel	15%	142.22	201 / 1335	0%	0	0 / 0
thymus	8%	29.24	50 / 653	7%	0.24	41 / 605
adipose	13%	140.63	162 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	9%	3.53	4 / 45
muscle	8%	36.60	63 / 803	0%	0	0 / 0
kidney	1%	4.34	1 / 89	2%	0.18	19 / 901
spleen	0%	1.49	1 / 241	0%	0	0 / 0
peripheral blood	0%	0.35	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0006915	Biological process	apoptotic process
GO_0030178	Biological process	negative regulation of Wnt signaling pathway
GO_0007601	Biological process	visual perception
GO_0007163	Biological process	establishment or maintenance of cell polarity
GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0035567	Biological process	non-canonical Wnt signaling pathway
GO_0030154	Biological process	cell differentiation
GO_0048546	Biological process	digestive tract morphogenesis
GO_0090090	Biological process	negative regulation of canonical Wnt signaling pathway
GO_2000051	Biological process	negative regulation of non-canonical Wnt signaling pathway
GO_0060070	Biological process	canonical Wnt signaling pathway
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0051898	Biological process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0009653	Biological process	anatomical structure morphogenesis
GO_0005615	Cellular component	extracellular space
GO_0017147	Molecular function	Wnt-protein binding

Gene name	SFRP5
Protein name	Secreted frizzled-related protein 5 (sFRP-5) (Frizzled-related protein 1b) (FRP-1b) (Secreted apoptosis-related protein 3) (SARP-3)
Synonyms	SARP3 FRP1B
Description	FUNCTION: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.
Accessions	Q5T4F7 ENST00000266066.4

SFRP5 report