CAMK2G report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051924Biological processregulation of calcium ion transport
GO_0030154Biological processcell differentiation
GO_0030073Biological processinsulin secretion
GO_0010975Biological processregulation of neuron projection development
GO_0014733Biological processregulation of skeletal muscle adaptation
GO_0007399Biological processnervous system development
GO_0016020Cellular componentmembrane
GO_0030666Cellular componentendocytic vesicle membrane
GO_0005954Cellular componentcalcium- and calmodulin-dependent protein kinase complex
GO_0005654Cellular componentnucleoplasm
GO_0043005Cellular componentneuron projection
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0033017Cellular componentsarcoplasmic reticulum membrane
GO_0042803Molecular functionprotein homodimerization activity
GO_0106310Molecular functionprotein serine kinase activity
GO_0042802Molecular functionidentical protein binding
GO_0005524Molecular functionATP binding
GO_0004683Molecular functioncalmodulin-dependent protein kinase activity
GO_0005516Molecular functioncalmodulin binding
GO_0005515Molecular functionprotein binding
GO_0004723Molecular functioncalcium-dependent protein serine/threonine phosphatase activity

IV. Literature review

[source]
Gene nameCAMK2G
Protein namecalcium/calmodulin-dependent protein kinase (EC 2.7.11.17)
Calcium/calmodulin dependent protein kinase II gamma
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma, isoform CRA_p (cDNA FLJ38257 fis, clone FCBBF3001235, highly similar to Calcium/calmodulin-dependent protein kinase type II gamma chain)
SynonymshCG_20541
CAMK
CAMKG
CAMK-II
DescriptionFUNCTION: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity . In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin . In the central nervous system, it is involved in the regulation of neurite formation and arborization . It may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity). .

AccessionsENST00000322680.7
ENST00000700396.1
ENST00000322635.7 [Q13555-5]
ENST00000700395.1
ENST00000680035.1 [Q13555-11]
A0A2Q3DQE3
ENST00000394762.7
A0A8V8TR68
ENST00000305762.11 [Q13555-4]
H0Y6G2
A0A8V8TQ60
ENST00000700392.1
B3KTH7
A0A8V8TR72
Q8WU40
Q5SWX3
A0A8V8TQW6
A0A804CJ50
ENST00000372765.5
A0A8V8TQ77
ENST00000700398.1
ENST00000474131.5
ENST00000700401.1
ENST00000351293.7 [Q13555-10]
ENST00000441192.2
A0A8V8TQ82
ENST00000700393.1
A0A8V8TPN2
ENST00000423381.6
ENST00000433289.5
Q13555