Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 18 studies | 49% ± 22% | |
glutamatergic neuron | 10 studies | 44% ± 20% | |
endothelial cell | 9 studies | 26% ± 8% | |
smooth muscle cell | 9 studies | 28% ± 9% | |
retinal rod cell | 7 studies | 26% ± 8% | |
oligodendrocyte precursor cell | 7 studies | 30% ± 12% | |
retinal cone cell | 6 studies | 30% ± 5% | |
GABAergic neuron | 6 studies | 51% ± 17% | |
neuron | 5 studies | 32% ± 11% | |
microglial cell | 5 studies | 23% ± 5% | |
retinal ganglion cell | 4 studies | 51% ± 24% | |
epithelial cell | 4 studies | 35% ± 17% | |
type I pneumocyte | 4 studies | 22% ± 5% | |
macrophage | 4 studies | 24% ± 5% | |
pericyte | 4 studies | 18% ± 2% | |
interneuron | 4 studies | 48% ± 23% | |
GABAergic interneuron | 3 studies | 24% ± 2% | |
retinal bipolar neuron | 3 studies | 19% ± 1% | |
OFF-bipolar cell | 3 studies | 27% ± 2% | |
ON-bipolar cell | 3 studies | 28% ± 10% | |
dendritic cell | 3 studies | 29% ± 4% | |
abnormal cell | 3 studies | 19% ± 2% | |
ependymal cell | 3 studies | 34% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 10372.95 | 21 / 21 | 100% | 28.74 | 504 / 504 |
intestine | 100% | 12739.58 | 966 / 966 | 100% | 21.38 | 527 / 527 |
esophagus | 100% | 9589.39 | 1441 / 1445 | 100% | 22.82 | 183 / 183 |
uterus | 100% | 7454.16 | 170 / 170 | 99% | 20.65 | 456 / 459 |
brain | 99% | 9426.46 | 2623 / 2642 | 100% | 60.52 | 705 / 705 |
prostate | 98% | 5943.50 | 241 / 245 | 100% | 21.42 | 501 / 502 |
lung | 97% | 3777.87 | 562 / 578 | 100% | 22.57 | 1155 / 1155 |
breast | 96% | 3087.66 | 442 / 459 | 99% | 17.75 | 1111 / 1118 |
thymus | 96% | 2946.14 | 628 / 653 | 99% | 12.47 | 596 / 605 |
kidney | 94% | 3003.24 | 84 / 89 | 96% | 11.96 | 863 / 901 |
skin | 96% | 2798.03 | 1733 / 1809 | 88% | 8.28 | 414 / 472 |
stomach | 81% | 4765.00 | 291 / 359 | 100% | 21.69 | 285 / 286 |
adrenal gland | 79% | 1817.41 | 205 / 258 | 95% | 25.43 | 219 / 230 |
ovary | 74% | 2119.80 | 133 / 180 | 99% | 13.93 | 426 / 430 |
liver | 39% | 745.90 | 88 / 226 | 90% | 8.71 | 364 / 406 |
pancreas | 21% | 396.49 | 70 / 328 | 99% | 21.51 | 176 / 178 |
spleen | 100% | 4767.59 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.91 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.60 | 1 / 1 |
blood vessel | 100% | 13938.56 | 1333 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 6929.99 | 801 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 10.22 | 27 / 29 |
adipose | 91% | 3416.72 | 1097 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 88% | 4299.74 | 822 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 68% | 5.34 | 54 / 80 |
heart | 35% | 667.57 | 300 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051924 | Biological process | regulation of calcium ion transport |
GO_0030154 | Biological process | cell differentiation |
GO_0030073 | Biological process | insulin secretion |
GO_0010975 | Biological process | regulation of neuron projection development |
GO_0014733 | Biological process | regulation of skeletal muscle adaptation |
GO_0007399 | Biological process | nervous system development |
GO_0016020 | Cellular component | membrane |
GO_0030666 | Cellular component | endocytic vesicle membrane |
GO_0005954 | Cellular component | calcium- and calmodulin-dependent protein kinase complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0043005 | Cellular component | neuron projection |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0033017 | Cellular component | sarcoplasmic reticulum membrane |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005524 | Molecular function | ATP binding |
GO_0004683 | Molecular function | calmodulin-dependent protein kinase activity |
GO_0005516 | Molecular function | calmodulin binding |
GO_0005515 | Molecular function | protein binding |
GO_0004723 | Molecular function | calcium-dependent protein serine/threonine phosphatase activity |
Gene name | CAMK2G |
Protein name | calcium/calmodulin-dependent protein kinase (EC 2.7.11.17) Calcium/calmodulin dependent protein kinase II gamma Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17) Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma, isoform CRA_p (cDNA FLJ38257 fis, clone FCBBF3001235, highly similar to Calcium/calmodulin-dependent protein kinase type II gamma chain) |
Synonyms | hCG_20541 CAMK CAMKG CAMK-II |
Description | FUNCTION: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity . In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin . In the central nervous system, it is involved in the regulation of neurite formation and arborization . It may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity). . |
Accessions | ENST00000322680.7 ENST00000700396.1 ENST00000322635.7 [Q13555-5] ENST00000700395.1 ENST00000680035.1 [Q13555-11] A0A2Q3DQE3 ENST00000394762.7 A0A8V8TR68 ENST00000305762.11 [Q13555-4] H0Y6G2 A0A8V8TQ60 ENST00000700392.1 B3KTH7 A0A8V8TR72 Q8WU40 Q5SWX3 A0A8V8TQW6 A0A804CJ50 ENST00000372765.5 A0A8V8TQ77 ENST00000700398.1 ENST00000474131.5 ENST00000700401.1 ENST00000351293.7 [Q13555-10] ENST00000441192.2 A0A8V8TQ82 ENST00000700393.1 A0A8V8TPN2 ENST00000423381.6 ENST00000433289.5 Q13555 |