Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 11 studies | 34% ± 23% | |
| myofibroblast cell | 5 studies | 37% ± 27% | |
| connective tissue cell | 4 studies | 38% ± 26% | |
| adventitial cell | 4 studies | 29% ± 15% | |
| smooth muscle cell | 4 studies | 35% ± 16% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| uterus | 4 studies | 26% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 88% | 9291.49 | 403 / 459 | 87% | 120.88 | 968 / 1118 |
| prostate | 76% | 2451.44 | 187 / 245 | 82% | 77.74 | 413 / 502 |
| ovary | 100% | 8959.63 | 180 / 180 | 55% | 49.96 | 238 / 430 |
| uterus | 96% | 21582.46 | 163 / 170 | 52% | 132.95 | 240 / 459 |
| lung | 70% | 2037.08 | 404 / 578 | 70% | 59.50 | 814 / 1155 |
| thymus | 69% | 2285.38 | 452 / 653 | 38% | 42.48 | 230 / 605 |
| pancreas | 12% | 192.93 | 40 / 328 | 89% | 182.86 | 158 / 178 |
| blood vessel | 99% | 5668.53 | 1321 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 81% | 2053.21 | 195 / 241 | 0% | 0 | 0 / 0 |
| bladder | 29% | 403.67 | 6 / 21 | 49% | 52.39 | 247 / 504 |
| stomach | 11% | 166.64 | 41 / 359 | 62% | 73.14 | 177 / 286 |
| intestine | 21% | 306.13 | 199 / 966 | 50% | 51.16 | 263 / 527 |
| adipose | 68% | 3173.38 | 815 / 1204 | 0% | 0 | 0 / 0 |
| esophagus | 26% | 605.12 | 377 / 1445 | 41% | 30.57 | 75 / 183 |
| adrenal gland | 47% | 657.37 | 121 / 258 | 6% | 2.25 | 13 / 230 |
| heart | 41% | 1020.35 | 357 / 861 | 0% | 0 | 0 / 0 |
| brain | 4% | 45.69 | 93 / 2642 | 36% | 20.53 | 253 / 705 |
| kidney | 22% | 463.89 | 20 / 89 | 17% | 7.89 | 149 / 901 |
| skin | 6% | 85.91 | 104 / 1809 | 29% | 21.84 | 135 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 20% | 13.79 | 9 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 6.72 | 4 / 29 |
| muscle | 13% | 205.81 | 106 / 803 | 0% | 0 | 0 / 0 |
| liver | 0% | 20.84 | 1 / 226 | 8% | 3.04 | 34 / 406 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.31 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0055062 | Biological process | phosphate ion homeostasis |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0045606 | Biological process | positive regulation of epidermal cell differentiation |
| GO_0060349 | Biological process | bone morphogenesis |
| GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
| GO_0030510 | Biological process | regulation of BMP signaling pathway |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_1902174 | Biological process | positive regulation of keratinocyte apoptotic process |
| GO_0043433 | Biological process | negative regulation of DNA-binding transcription factor activity |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_0002092 | Biological process | positive regulation of receptor internalization |
| GO_0060070 | Biological process | canonical Wnt signaling pathway |
| GO_2000051 | Biological process | negative regulation of non-canonical Wnt signaling pathway |
| GO_0030178 | Biological process | negative regulation of Wnt signaling pathway |
| GO_0009725 | Biological process | response to hormone |
| GO_0030154 | Biological process | cell differentiation |
| GO_2000119 | Biological process | negative regulation of sodium-dependent phosphate transport |
| GO_0035567 | Biological process | non-canonical Wnt signaling pathway |
| GO_0043065 | Biological process | positive regulation of apoptotic process |
| GO_0005615 | Cellular component | extracellular space |
| GO_0009986 | Cellular component | cell surface |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0017147 | Molecular function | Wnt-protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SFRP4 |
| Protein name | Secreted frizzled related protein 4 Secreted frizzled-related protein 4 (sFRP-4) (Frizzled protein, human endometrium) (FrpHE) |
| Synonyms | FRPHE |
| Description | FUNCTION: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake . . |
| Accessions | ENST00000447200.2 Q6FHJ7 C9JMJ2 ENST00000436072.7 |
