HES4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007399Biological processnervous system development
GO_0030154Biological processcell differentiation
GO_0009952Biological processanterior/posterior pattern specification
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameHES4
Protein nameTranscription factor HES-4 (hHES4) (Class B basic helix-loop-helix protein 42) (bHLHb42) (Hairy and enhancer of split 4) (bHLH factor Hes4)
Hes family bHLH transcription factor 4
SynonymsBHLHB42
DescriptionFUNCTION: Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3' (By similarity). .

AccessionsD6REB3
ENST00000428771.6
ENST00000484667.2
Q9HCC6
ENST00000304952.11
E9PB28