Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 3 studies | 23% ± 4% | |
| mast cell | 3 studies | 23% ± 5% |
Insufficient scRNA-seq data for expression of EDARADD at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 93% | 144.68 | 229 / 245 | 80% | 7.74 | 403 / 502 |
| bladder | 90% | 234.05 | 19 / 21 | 66% | 11.70 | 333 / 504 |
| thymus | 99% | 152.25 | 648 / 653 | 46% | 2.78 | 281 / 605 |
| pancreas | 98% | 76.84 | 322 / 328 | 40% | 3.46 | 71 / 178 |
| breast | 64% | 125.40 | 293 / 459 | 69% | 10.29 | 771 / 1118 |
| kidney | 93% | 56.82 | 83 / 89 | 9% | 0.61 | 85 / 901 |
| skin | 85% | 137.76 | 1540 / 1809 | 17% | 0.73 | 80 / 472 |
| lung | 55% | 19.28 | 318 / 578 | 47% | 5.06 | 540 / 1155 |
| esophagus | 50% | 68.66 | 726 / 1445 | 51% | 4.29 | 93 / 183 |
| ureter | 0% | 0 | 0 / 0 | 100% | 13.74 | 1 / 1 |
| spleen | 97% | 44.09 | 234 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 16.91 | 43 / 45 |
| stomach | 80% | 191.03 | 288 / 359 | 10% | 0.85 | 29 / 286 |
| uterus | 23% | 6.63 | 39 / 170 | 64% | 6.82 | 293 / 459 |
| ovary | 36% | 10.94 | 65 / 180 | 34% | 2.13 | 146 / 430 |
| peripheral blood | 48% | 34.73 | 447 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 38% | 1.27 | 30 / 80 |
| heart | 36% | 16.86 | 308 / 861 | 0% | 0 | 0 / 0 |
| adipose | 33% | 13.99 | 403 / 1204 | 0% | 0 | 0 / 0 |
| intestine | 17% | 5.38 | 169 / 966 | 4% | 0.23 | 23 / 527 |
| lymph node | 0% | 0 | 0 / 0 | 21% | 0.75 | 6 / 29 |
| liver | 5% | 1.27 | 11 / 226 | 13% | 0.82 | 53 / 406 |
| blood vessel | 16% | 4.93 | 219 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 6% | 1.36 | 15 / 258 | 1% | 0.14 | 2 / 230 |
| brain | 2% | 0.56 | 56 / 2642 | 1% | 0.10 | 10 / 705 |
| muscle | 0% | 0.03 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007165 | Biological process | signal transduction |
| GO_0030154 | Biological process | cell differentiation |
| GO_0005829 | Cellular component | cytosol |
| GO_0005515 | Molecular function | protein binding |
| Gene name | EDARADD |
| Protein name | Ectodysplasin-A receptor-associated adapter protein (EDAR-associated death domain protein) (Protein crinkled homolog) EDAR-associated death domain phosphopyruvate hydratase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) EDAR associated death domain Ectodysplasin-A receptor-associated adapter protein isoform B |
| Synonyms | hCG_1640319 |
| Description | FUNCTION: Adapter protein that interacts with EDAR DEATH domain and couples the receptor to EDA signaling pathway during morphogenesis of ectodermal organs. Mediates the activation of NF-kappa-B. . |
| Accessions | ENST00000637660.1 A0A2R8Y5E0 G8FL38 ENST00000334232.9 [Q8WWZ3-1] ENST00000359362.6 [Q8WWZ3-2] A0A1B0GV26 A0A0K0VQ49 Q8WWZ3 B1AL55 ENST00000642595.1 ENST00000439430.5 L0R849 |