ERG report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ERG at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006468Biological processprotein phosphorylation
GO_0030154Biological processcell differentiation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_1990904Cellular componentribonucleoprotein complex
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003682Molecular functionchromatin binding

IV. Literature review

[source]
Gene nameERG
Protein nameETS transcription factor ERG
Transcriptional regulator ERG (Transforming protein ERG)
ETS transcription factor ERG (Erythroblast transformation-specific transcription factor ERG variant 10)
TMPRSS2-ERG prostate cancer specific isoform 1
Synonyms
DescriptionFUNCTION: Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.

AccessionsA8MZ24
P11308
ENST00000398911.5 [P11308-1]
ENST00000417133.6 [P11308-3]
A0A0C4DG41
ENST00000398910.5
ENST00000398905.5
A8MX39
B2Y833
ENST00000288319.12 [P11308-4]
ENST00000453032.6
B5MDW0
ENST00000442448.5 [P11308-1]
ENST00000398919.6 [P11308-3]
ENST00000398907.5
ENST00000398897.5 [P11308-2]