Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 47 studies | 42% ± 17% | |
endothelial cell of lymphatic vessel | 16 studies | 38% ± 17% | |
vein endothelial cell | 14 studies | 41% ± 20% | |
capillary endothelial cell | 13 studies | 34% ± 14% | |
endothelial cell of artery | 13 studies | 35% ± 14% | |
endothelial cell of vascular tree | 13 studies | 34% ± 19% | |
mast cell | 8 studies | 21% ± 6% | |
pro-B cell | 5 studies | 31% ± 12% | |
hematopoietic stem cell | 4 studies | 19% ± 3% | |
endothelial cell of sinusoid | 3 studies | 40% ± 19% | |
glomerular endothelial cell | 3 studies | 22% ± 1% |
Insufficient scRNA-seq data for expression of ERG at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 4459.66 | 459 / 459 | 93% | 7.40 | 1038 / 1118 |
thymus | 100% | 2287.76 | 651 / 653 | 93% | 7.28 | 563 / 605 |
lung | 100% | 4319.38 | 578 / 578 | 92% | 6.44 | 1065 / 1155 |
prostate | 98% | 1431.72 | 239 / 245 | 94% | 65.72 | 472 / 502 |
esophagus | 92% | 1185.35 | 1336 / 1445 | 89% | 4.96 | 163 / 183 |
uterus | 100% | 2666.46 | 170 / 170 | 76% | 5.14 | 349 / 459 |
kidney | 100% | 1762.25 | 89 / 89 | 74% | 13.78 | 664 / 901 |
adrenal gland | 87% | 788.53 | 225 / 258 | 81% | 5.66 | 186 / 230 |
bladder | 95% | 1461.00 | 20 / 21 | 63% | 3.17 | 318 / 504 |
intestine | 90% | 1153.75 | 874 / 966 | 62% | 3.20 | 328 / 527 |
stomach | 76% | 754.02 | 274 / 359 | 73% | 4.29 | 209 / 286 |
brain | 44% | 364.15 | 1162 / 2642 | 91% | 4.22 | 644 / 705 |
ovary | 73% | 825.31 | 131 / 180 | 52% | 2.17 | 223 / 430 |
skin | 59% | 653.89 | 1073 / 1809 | 53% | 2.64 | 249 / 472 |
pancreas | 15% | 106.59 | 50 / 328 | 92% | 7.71 | 163 / 178 |
adipose | 100% | 4926.05 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5412.54 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 5015.03 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 96% | 1299.92 | 830 / 861 | 0% | 0 | 0 / 0 |
liver | 31% | 243.09 | 71 / 226 | 64% | 2.50 | 258 / 406 |
tonsil | 0% | 0 | 0 / 0 | 82% | 5.24 | 37 / 45 |
muscle | 77% | 654.24 | 616 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 62% | 1.85 | 18 / 29 |
eye | 0% | 0 | 0 / 0 | 39% | 1.33 | 31 / 80 |
peripheral blood | 8% | 65.06 | 72 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0006468 | Biological process | protein phosphorylation |
GO_0030154 | Biological process | cell differentiation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_1990904 | Cellular component | ribonucleoprotein complex |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003682 | Molecular function | chromatin binding |
Gene name | ERG |
Protein name | ETS transcription factor ERG Transcriptional regulator ERG (Transforming protein ERG) ETS transcription factor ERG (Erythroblast transformation-specific transcription factor ERG variant 10) TMPRSS2-ERG prostate cancer specific isoform 1 |
Synonyms | |
Description | FUNCTION: Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. |
Accessions | A8MZ24 P11308 ENST00000398911.5 [P11308-1] ENST00000417133.6 [P11308-3] A0A0C4DG41 ENST00000398910.5 ENST00000398905.5 A8MX39 B2Y833 ENST00000288319.12 [P11308-4] ENST00000453032.6 B5MDW0 ENST00000442448.5 [P11308-1] ENST00000398919.6 [P11308-3] ENST00000398907.5 ENST00000398897.5 [P11308-2] |