Insufficient scRNA-seq data for expression of PLK5 at single-cell level.
Insufficient scRNA-seq data for expression of PLK5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 825.03 | 2577 / 2642 | 58% | 1.66 | 411 / 705 |
| uterus | 88% | 363.46 | 150 / 170 | 5% | 0.14 | 25 / 459 |
| prostate | 64% | 86.48 | 158 / 245 | 7% | 0.10 | 33 / 502 |
| ovary | 46% | 45.59 | 82 / 180 | 1% | 0.01 | 3 / 430 |
| breast | 41% | 52.33 | 186 / 459 | 2% | 0.03 | 18 / 1118 |
| intestine | 29% | 23.43 | 278 / 966 | 4% | 0.10 | 22 / 527 |
| esophagus | 22% | 17.17 | 325 / 1445 | 9% | 0.17 | 17 / 183 |
| skin | 23% | 17.58 | 414 / 1809 | 1% | 0.02 | 4 / 472 |
| thymus | 12% | 8.71 | 76 / 653 | 4% | 0.32 | 26 / 605 |
| stomach | 5% | 2.99 | 17 / 359 | 8% | 0.24 | 23 / 286 |
| bladder | 5% | 3.10 | 1 / 21 | 5% | 0.09 | 25 / 504 |
| eye | 0% | 0 | 0 / 0 | 9% | 0.14 | 7 / 80 |
| adipose | 7% | 5.31 | 84 / 1204 | 0% | 0 | 0 / 0 |
| liver | 4% | 2.35 | 8 / 226 | 2% | 0.03 | 8 / 406 |
| adrenal gland | 3% | 5.37 | 9 / 258 | 2% | 0.08 | 4 / 230 |
| lung | 2% | 1.19 | 11 / 578 | 3% | 0.07 | 38 / 1155 |
| kidney | 3% | 2.98 | 3 / 89 | 2% | 0.43 | 16 / 901 |
| blood vessel | 5% | 6.17 | 68 / 1335 | 0% | 0 | 0 / 0 |
| heart | 4% | 4.92 | 34 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.05 | 1 / 29 |
| pancreas | 1% | 0.52 | 3 / 328 | 2% | 0.05 | 3 / 178 |
| muscle | 2% | 2.27 | 19 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 0.51 | 8 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0002357 | Biological process | defense response to tumor cell |
| GO_2000045 | Biological process | regulation of G1/S transition of mitotic cell cycle |
| GO_0042981 | Biological process | regulation of apoptotic process |
| GO_0051301 | Biological process | cell division |
| GO_0030154 | Biological process | cell differentiation |
| GO_0071363 | Biological process | cellular response to growth factor stimulus |
| GO_0010976 | Biological process | positive regulation of neuron projection development |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005524 | Molecular function | ATP binding |
| GO_0004672 | Molecular function | protein kinase activity |
| Gene name | PLK5 |
| Protein name | Inactive serine/threonine-protein kinase PLK5 (Polo-like kinase 5) (PLK-5) Polo like kinase 5 (inactive) |
| Synonyms | PLK5P FG060302 |
| Description | FUNCTION: Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation. . |
| Accessions | ENST00000673896.1 [Q496M5-2] A0A286YFL1 ENST00000673796.1 [Q496M5-1] ENST00000673648.1 A0A669KBC1 ENST00000334770.9 [Q496M5-1] ENST00000642079.2 ENST00000454744.7 [Q496M5-1] ENST00000588430.3 [Q496M5-2] Q496M5 |