Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brush cell | 3 studies | 29% ± 9% |
Insufficient scRNA-seq data for expression of ANKS4B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 1462.58 | 226 / 226 | 91% | 14.21 | 369 / 406 |
| intestine | 73% | 1308.67 | 706 / 966 | 95% | 32.81 | 500 / 527 |
| kidney | 98% | 624.93 | 87 / 89 | 69% | 10.22 | 625 / 901 |
| pancreas | 97% | 43.29 | 317 / 328 | 67% | 10.15 | 120 / 178 |
| stomach | 63% | 46.59 | 227 / 359 | 92% | 25.71 | 262 / 286 |
| esophagus | 2% | 1.19 | 29 / 1445 | 45% | 7.82 | 83 / 183 |
| bladder | 19% | 2.10 | 4 / 21 | 24% | 8.88 | 123 / 504 |
| brain | 34% | 26.37 | 902 / 2642 | 0% | 0 | 0 / 705 |
| lung | 3% | 0.44 | 19 / 578 | 19% | 2.99 | 222 / 1155 |
| skin | 15% | 2.25 | 274 / 1809 | 0% | 0 | 0 / 472 |
| prostate | 13% | 1.91 | 31 / 245 | 0% | 0.01 | 1 / 502 |
| uterus | 4% | 0.65 | 6 / 170 | 7% | 1.66 | 34 / 459 |
| heart | 10% | 1.38 | 85 / 861 | 0% | 0 | 0 / 0 |
| adipose | 6% | 1.00 | 71 / 1204 | 0% | 0 | 0 / 0 |
| breast | 5% | 5.73 | 24 / 459 | 0% | 0.03 | 5 / 1118 |
| peripheral blood | 5% | 1.90 | 48 / 929 | 0% | 0 | 0 / 0 |
| ovary | 4% | 0.90 | 8 / 180 | 0% | 0.09 | 2 / 430 |
| blood vessel | 2% | 0.37 | 33 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 2% | 1.11 | 4 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 1% | 0.16 | 2 / 258 | 1% | 0.09 | 2 / 230 |
| muscle | 1% | 0.17 | 10 / 803 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0.07 | 3 / 653 | 0% | 0 | 0 / 605 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1904106 | Biological process | protein localization to microvillus |
| GO_1904970 | Biological process | brush border assembly |
| GO_0030154 | Biological process | cell differentiation |
| GO_0034976 | Biological process | response to endoplasmic reticulum stress |
| GO_0065003 | Biological process | protein-containing complex assembly |
| GO_0005903 | Cellular component | brush border |
| GO_0005902 | Cellular component | microvillus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ANKS4B |
| Protein name | Ankyrin repeat and SAM domain-containing protein 4B (Harmonin-interacting ankyrin repeat-containing protein) (Harp) |
| Synonyms | HARP |
| Description | FUNCTION: As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. Plays a role in assembly of the complex . May play a role in cellular response to endoplasmic reticulum stress (By similarity). . |
| Accessions | ENST00000639229.2 Q8N8V4 ENST00000311620.7 |