ABCB5 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ABCB5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	53%	83.68	953 / 1809	71%	24.89	334 / 472
eye	0%	0	0 / 0	100%	59.21	80 / 80
breast	92%	383.61	421 / 459	4%	0.08	45 / 1118
adipose	92%	300.68	1103 / 1204	0%	0	0 / 0
intestine	73%	112.09	707 / 966	0%	0.01	2 / 527
uterus	58%	63.65	98 / 170	3%	1.13	13 / 459
bladder	57%	52.76	12 / 21	1%	0.01	5 / 504
stomach	34%	33.48	123 / 359	2%	0.05	5 / 286
blood vessel	24%	19.60	314 / 1335	0%	0	0 / 0
esophagus	19%	14.40	277 / 1445	1%	0.03	2 / 183
lung	15%	7.06	87 / 578	1%	0.03	17 / 1155
prostate	12%	6.11	29 / 245	2%	0.16	8 / 502
kidney	7%	5.36	6 / 89	4%	2.05	37 / 901
ovary	8%	6.29	15 / 180	2%	0.04	10 / 430
muscle	9%	4.26	74 / 803	0%	0	0 / 0
thymus	9%	3.42	58 / 653	0%	0	0 / 605
liver	1%	0.33	3 / 226	5%	0.37	21 / 406
adrenal gland	2%	0.86	5 / 258	3%	0.26	8 / 230
heart	4%	1.63	34 / 861	0%	0	0 / 0
pancreas	2%	0.41	5 / 328	1%	0.01	2 / 178
peripheral blood	2%	0.78	20 / 929	0%	0	0 / 0
spleen	2%	0.70	5 / 241	0%	0	0 / 0
brain	0%	0.12	8 / 2642	0%	0.01	2 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0042908	Biological process	xenobiotic transport
GO_0055085	Biological process	transmembrane transport
GO_0042391	Biological process	regulation of membrane potential
GO_0030154	Biological process	cell differentiation
GO_0001654	Biological process	eye development
GO_0016020	Cellular component	membrane
GO_0005886	Cellular component	plasma membrane
GO_0008559	Molecular function	ABC-type xenobiotic transporter activity
GO_0042626	Molecular function	ATPase-coupled transmembrane transporter activity
GO_0015562	Molecular function	efflux transmembrane transporter activity
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0005524	Molecular function	ATP binding

Gene name	ABCB5
Protein name	ATP-binding cassette sub-family B member 5 (ABCB5 P-gp) (P-glycoprotein ABCB5) (EC 7.6.2.2) ATP-binding cassette subfamily B member 5 ATP binding cassette subfamily B member 5
Synonyms
Description	FUNCTION: Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells . Specifically present in limbal stem cells, where it plays a key role in corneal development and repair (By similarity). .
Accessions	ENST00000258738.10 [Q2M3G0-1] ENST00000406935.5 [Q2M3G0-3] ENST00000441315.1 H7C165 Q2M3G0 ENST00000404938.7 [Q2M3G0-4] A0ASV4 ENST00000443026.6 [Q2M3G0-2]

ABCB5 report