SEPTIN6 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	36 studies	43% ± 13%	Explore
T cell	35 studies	41% ± 16%	Explore
natural killer cell	35 studies	36% ± 12%	Explore
CD8-positive, alpha-beta T cell	33 studies	41% ± 18%	Explore
CD4-positive, alpha-beta T cell	30 studies	45% ± 17%	Explore
regulatory T cell	26 studies	52% ± 14%	Explore
conventional dendritic cell	22 studies	35% ± 17%	Explore
plasmacytoid dendritic cell	18 studies	51% ± 16%	Explore
memory B cell	17 studies	47% ± 9%	Explore
naive B cell	17 studies	41% ± 10%	Explore
mature NK T cell	15 studies	40% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	45% ± 12%	Explore
plasma cell	15 studies	35% ± 12%	Explore
dendritic cell	14 studies	39% ± 19%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	45% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	40% ± 11%	Explore
gamma-delta T cell	13 studies	46% ± 17%	Explore
mucosal invariant T cell	12 studies	36% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	49% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	11 studies	46% ± 15%	Explore
monocyte	10 studies	22% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	51% ± 17%	Explore
non-classical monocyte	10 studies	28% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	39% ± 14%	Explore
plasmablast	8 studies	40% ± 24%	Explore
platelet	8 studies	27% ± 8%	Explore
T follicular helper cell	8 studies	49% ± 13%	Explore
hematopoietic stem cell	8 studies	71% ± 15%	Explore
innate lymphoid cell	7 studies	30% ± 11%	Explore
leukocyte	7 studies	30% ± 9%	Explore
precursor B cell	7 studies	61% ± 12%	Explore
pericyte	7 studies	20% ± 3%	Explore
endothelial cell of lymphatic vessel	7 studies	23% ± 6%	Explore
macrophage	7 studies	28% ± 11%	Explore
microglial cell	7 studies	28% ± 10%	Explore
CD4-positive helper T cell	6 studies	33% ± 12%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	52% ± 23%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	50% ± 16%	Explore
endothelial cell	6 studies	21% ± 4%	Explore
glutamatergic neuron	6 studies	46% ± 26%	Explore
immature B cell	6 studies	60% ± 17%	Explore
neuron	6 studies	42% ± 17%	Explore
retina horizontal cell	6 studies	41% ± 13%	Explore
GABAergic neuron	6 studies	41% ± 24%	Explore
interneuron	6 studies	33% ± 15%	Explore
hematopoietic precursor cell	5 studies	68% ± 20%	Explore
exhausted T cell	5 studies	52% ± 13%	Explore
lymphocyte	5 studies	49% ± 12%	Explore
pro-B cell	5 studies	63% ± 10%	Explore
T-helper 17 cell	5 studies	54% ± 12%	Explore
group 3 innate lymphoid cell	5 studies	67% ± 12%	Explore
double negative thymocyte	5 studies	67% ± 18%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	37% ± 12%	Explore
fibroblast	4 studies	20% ± 5%	Explore
smooth muscle cell	4 studies	24% ± 7%	Explore
myeloid cell	4 studies	26% ± 11%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	52% ± 16%	Explore
oligodendrocyte precursor cell	4 studies	35% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	37% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	50% ± 21%	Explore
classical monocyte	3 studies	33% ± 12%	Explore
mononuclear phagocyte	3 studies	23% ± 7%	Explore
connective tissue cell	3 studies	35% ± 11%	Explore
abnormal cell	3 studies	32% ± 10%	Explore
megakaryocyte	3 studies	30% ± 10%	Explore
myofibroblast cell	3 studies	24% ± 7%	Explore
retinal cone cell	3 studies	23% ± 6%	Explore
germinal center B cell	3 studies	51% ± 4%	Explore
oligodendrocyte	3 studies	28% ± 7%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	15 studies	37% ± 14%	Explore
lung	8 studies	19% ± 3%	Explore
brain	6 studies	36% ± 21%	Explore
bone marrow	4 studies	35% ± 15%	Explore
liver	4 studies	25% ± 4%	Explore
intestine	3 studies	22% ± 2%	Explore
lymph node	3 studies	49% ± 3%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	12832.24	258 / 258	100%	80.96	229 / 230
prostate	99%	2070.10	243 / 245	100%	22.49	501 / 502
breast	98%	2042.86	450 / 459	99%	29.93	1108 / 1118
lung	99%	2708.35	575 / 578	97%	22.09	1119 / 1155
uterus	100%	1733.14	170 / 170	96%	27.15	439 / 459
kidney	100%	2702.18	89 / 89	95%	18.98	859 / 901
intestine	100%	6632.37	964 / 966	93%	15.88	488 / 527
stomach	99%	2673.55	355 / 359	91%	21.19	260 / 286
liver	96%	1631.18	217 / 226	93%	26.51	376 / 406
thymus	93%	1563.26	607 / 653	96%	43.81	578 / 605
esophagus	96%	3217.11	1391 / 1445	92%	15.51	168 / 183
ovary	96%	1593.07	173 / 180	92%	16.69	394 / 430
bladder	100%	2082.62	21 / 21	87%	14.38	436 / 504
skin	89%	1364.91	1616 / 1809	94%	28.98	445 / 472
brain	86%	2149.74	2259 / 2642	86%	12.64	605 / 705
pancreas	11%	119.80	37 / 328	96%	22.93	170 / 178
lymph node	0%	0	0 / 0	100%	166.99	29 / 29
spleen	100%	10369.71	241 / 241	0%	0	0 / 0
peripheral blood	99%	11723.86	920 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	21.62	44 / 45
adipose	97%	1786.31	1164 / 1204	0%	0	0 / 0
blood vessel	94%	1699.90	1254 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	93%	13.49	74 / 80
heart	84%	1396.24	720 / 861	0%	0	0 / 0
muscle	4%	32.01	30 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1