UNC45A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of UNC45A at tissue level.

III. Associated gene sets

GO_0030154Biological processcell differentiation
GO_0061077Biological processchaperone-mediated protein folding
GO_0007517Biological processmuscle organ development
GO_0016607Cellular componentnuclear speck
GO_0005829Cellular componentcytosol
GO_0005794Cellular componentGolgi apparatus
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005737Cellular componentcytoplasm
GO_0045296Molecular functioncadherin binding
GO_0005515Molecular functionprotein binding
GO_0051879Molecular functionHsp90 protein binding

IV. Literature review

[source]
Gene nameUNC45A
Protein nameUnc-45 myosin chaperone A
Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1)
SynonymsSMAP1
DescriptionFUNCTION: Acts as a co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity). .

AccessionsA0A5F9ZI32
ENST00000639885.1
Q9H3U1
ENST00000672480.1
A0A1W2PNX8
ENST00000418476.2 [Q9H3U1-1]
ENST00000394275.7 [Q9H3U1-2]
A0A5F9ZI17
ENST00000480470.5