I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 10 studies | 21% ± 6% | |
| smooth muscle cell | 6 studies | 32% ± 13% | |
| hepatocyte | 3 studies | 38% ± 28% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 10 studies | 21% ± 6% | |
| smooth muscle cell | 6 studies | 32% ± 13% | |
| hepatocyte | 3 studies | 38% ± 28% |
Insufficient scRNA-seq data for expression of FST at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 99% | 3532.25 | 223 / 226 | 91% | 129.58 | 370 / 406 |
| breast | 100% | 1644.25 | 459 / 459 | 72% | 26.11 | 805 / 1118 |
| esophagus | 87% | 569.73 | 1257 / 1445 | 66% | 53.07 | 121 / 183 |
| prostate | 97% | 1403.09 | 238 / 245 | 53% | 8.22 | 264 / 502 |
| lung | 93% | 816.03 | 540 / 578 | 51% | 43.22 | 587 / 1155 |
| uterus | 80% | 576.78 | 136 / 170 | 63% | 50.28 | 288 / 459 |
| skin | 100% | 2020.70 | 1806 / 1809 | 39% | 20.83 | 186 / 472 |
| bladder | 86% | 1224.95 | 18 / 21 | 51% | 29.51 | 259 / 504 |
| ovary | 66% | 948.33 | 118 / 180 | 53% | 19.03 | 226 / 430 |
| stomach | 96% | 890.13 | 344 / 359 | 15% | 5.57 | 43 / 286 |
| intestine | 94% | 874.44 | 911 / 966 | 14% | 2.51 | 72 / 527 |
| ureter | 0% | 0 | 0 / 0 | 100% | 37.36 | 1 / 1 |
| adipose | 99% | 2049.08 | 1194 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 67.29 | 43 / 45 |
| blood vessel | 95% | 1384.20 | 1264 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 77% | 562.40 | 198 / 258 | 18% | 5.31 | 41 / 230 |
| thymus | 79% | 416.82 | 513 / 653 | 10% | 3.79 | 61 / 605 |
| heart | 60% | 444.81 | 517 / 861 | 0% | 0 | 0 / 0 |
| muscle | 57% | 504.59 | 455 / 803 | 0% | 0 | 0 / 0 |
| pancreas | 7% | 32.55 | 24 / 328 | 42% | 10.27 | 75 / 178 |
| kidney | 34% | 223.48 | 30 / 89 | 8% | 3.14 | 71 / 901 |
| brain | 3% | 14.49 | 81 / 2642 | 15% | 3.19 | 109 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.67 | 2 / 29 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.12 | 1 / 80 |
| spleen | 1% | 5.31 | 3 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.80 | 3 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042475 | Biological process | odontogenesis of dentin-containing tooth |
| GO_0002244 | Biological process | hematopoietic progenitor cell differentiation |
| GO_0036305 | Biological process | ameloblast differentiation |
| GO_0030510 | Biological process | regulation of BMP signaling pathway |
| GO_0031069 | Biological process | hair follicle morphogenesis |
| GO_0007275 | Biological process | multicellular organism development |
| GO_0007276 | Biological process | gamete generation |
| GO_0014070 | Biological process | response to organic cyclic compound |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0032926 | Biological process | negative regulation of activin receptor signaling pathway |
| GO_0051798 | Biological process | positive regulation of hair follicle development |
| GO_0030509 | Biological process | BMP signaling pathway |
| GO_0030857 | Biological process | negative regulation of epithelial cell differentiation |
| GO_0030154 | Biological process | cell differentiation |
| GO_0001501 | Biological process | skeletal system development |
| GO_0008585 | Biological process | female gonad development |
| GO_0043616 | Biological process | keratinocyte proliferation |
| GO_0007389 | Biological process | pattern specification process |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0038102 | Molecular function | activin receptor antagonist activity |
| GO_0048185 | Molecular function | activin binding |
| GO_0043395 | Molecular function | heparan sulfate proteoglycan binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | FST |
| Protein name | Follistatin (Activin-binding protein) Follistatin Follistatin (FS) (Activin-binding protein) |
| Synonyms | |
| Description | FUNCTION: Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). FUNCTION: Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). . FUNCTION: Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). . |
| Accessions | ENST00000256759.8 [P19883-1] ENST00000396947.7 [P19883-2] Q6FHE1 P19883 ENST00000504226.5 H0YA75 ENST00000497789.2 H0YAF9 |
