Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 15 studies | 26% ± 9% | |
microglial cell | 12 studies | 31% ± 12% | |
oligodendrocyte precursor cell | 9 studies | 27% ± 10% | |
oligodendrocyte | 9 studies | 30% ± 14% | |
GABAergic neuron | 8 studies | 35% ± 21% | |
adipocyte | 8 studies | 27% ± 4% | |
astrocyte | 7 studies | 35% ± 19% | |
glutamatergic neuron | 6 studies | 42% ± 24% | |
macrophage | 6 studies | 32% ± 5% | |
fibroblast | 6 studies | 24% ± 5% | |
T cell | 5 studies | 21% ± 3% | |
endothelial cell of lymphatic vessel | 5 studies | 29% ± 6% | |
pericyte | 5 studies | 22% ± 7% | |
type I pneumocyte | 5 studies | 24% ± 6% | |
neuron | 4 studies | 38% ± 19% | |
epithelial cell | 4 studies | 26% ± 16% | |
retinal cone cell | 4 studies | 22% ± 4% | |
retinal rod cell | 4 studies | 26% ± 6% | |
smooth muscle cell | 4 studies | 19% ± 2% | |
interneuron | 4 studies | 45% ± 22% | |
mast cell | 3 studies | 21% ± 4% | |
myeloid cell | 3 studies | 20% ± 4% | |
hepatocyte | 3 studies | 32% ± 11% | |
neural progenitor cell | 3 studies | 27% ± 13% | |
alveolar macrophage | 3 studies | 23% ± 4% | |
monocyte | 3 studies | 20% ± 2% | |
type II pneumocyte | 3 studies | 18% ± 3% | |
lymphocyte | 3 studies | 29% ± 9% | |
transit amplifying cell | 3 studies | 42% ± 31% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 373.48 | 1445 / 1445 | 100% | 6.54 | 183 / 183 |
lung | 100% | 425.25 | 577 / 578 | 100% | 4.53 | 1151 / 1155 |
breast | 100% | 599.79 | 459 / 459 | 99% | 5.69 | 1108 / 1118 |
uterus | 100% | 595.50 | 170 / 170 | 99% | 4.30 | 453 / 459 |
thymus | 100% | 517.14 | 653 / 653 | 98% | 3.51 | 595 / 605 |
brain | 98% | 222.75 | 2596 / 2642 | 100% | 3.54 | 702 / 705 |
intestine | 100% | 412.36 | 966 / 966 | 98% | 3.97 | 514 / 527 |
bladder | 100% | 496.24 | 21 / 21 | 97% | 3.97 | 491 / 504 |
prostate | 100% | 437.46 | 245 / 245 | 97% | 3.22 | 489 / 502 |
skin | 100% | 560.61 | 1809 / 1809 | 97% | 6.17 | 459 / 472 |
stomach | 100% | 309.10 | 358 / 359 | 97% | 4.64 | 278 / 286 |
pancreas | 99% | 194.03 | 325 / 328 | 98% | 3.51 | 174 / 178 |
ovary | 100% | 452.83 | 180 / 180 | 95% | 2.38 | 410 / 430 |
adrenal gland | 100% | 285.26 | 258 / 258 | 94% | 2.51 | 217 / 230 |
kidney | 100% | 316.20 | 89 / 89 | 94% | 3.05 | 848 / 901 |
liver | 98% | 195.48 | 222 / 226 | 69% | 1.50 | 280 / 406 |
adipose | 100% | 594.30 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 486.01 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 361.00 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 5.61 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.10 | 1 / 1 |
muscle | 100% | 278.06 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 96% | 248.93 | 829 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 2.79 | 27 / 29 |
eye | 0% | 0 | 0 / 0 | 86% | 2.79 | 69 / 80 |
peripheral blood | 62% | 203.79 | 578 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007420 | Biological process | brain development |
GO_0042273 | Biological process | ribosomal large subunit biogenesis |
GO_0007283 | Biological process | spermatogenesis |
GO_0030154 | Biological process | cell differentiation |
GO_0005819 | Cellular component | spindle |
GO_0005737 | Cellular component | cytoplasm |
GO_0005739 | Cellular component | mitochondrion |
GO_1990275 | Molecular function | preribosome binding |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | AFG2A |
Protein name | vesicle-fusing ATPase (EC 3.6.4.6) ATPase family gene 2 protein homolog A (EC 3.6.4.10) (AFG2 AAA ATPase homolog A) (Ribosome biogenesis protein SPATA5) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5) |
Synonyms | SPAF SPATA5 |
Description | FUNCTION: ATP-dependent chaperone, which plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles . Acts together with AFG2B, AIRIM and CINP . May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity). . |
Accessions | A0A6Q8PGU6 ENST00000274008.5 [Q8NB90-1] ENST00000675612.1 Q8NB90 |