FOXJ2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FOXJ2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FOXJ2 at tissue level.

III. Associated gene sets

GO_0016525Biological processnegative regulation of angiogenesis
GO_0007283Biological processspermatogenesis
GO_0007141Biological processmale meiosis I
GO_0030154Biological processcell differentiation
GO_0110059Biological processnegative regulation of blood vessel endothelial cell differentiation
GO_1904707Biological processpositive regulation of vascular associated smooth muscle cell proliferation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0001650Cellular componentfibrillar center
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameFOXJ2
Protein nameForkhead box protein J2 (Fork head homologous X)
SynonymsFHX
DescriptionFUNCTION: [Isoform FOXJ2.L]: Transcriptional activator. Able to bind to two different type of DNA binding sites. More effective than isoform FOXJ2.S in transcriptional activation . Plays an important role in spermatogenesis, especially in spermatocyte meiosis (By similarity). .; FUNCTION: [Isoform FOXJ2.S]: Transcriptional activator. .

AccessionsENST00000162391.8 [Q9P0K8-1]
ENST00000428177.2 [Q9P0K8-2]
Q9P0K8