Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 16 studies | 42% ± 19% |
Insufficient scRNA-seq data for expression of DLEC1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 495.41 | 653 / 653 | 54% | 1.35 | 326 / 605 |
brain | 73% | 338.41 | 1931 / 2642 | 63% | 2.39 | 443 / 705 |
lung | 99% | 1803.70 | 573 / 578 | 36% | 2.21 | 417 / 1155 |
ovary | 99% | 373.56 | 178 / 180 | 31% | 1.12 | 134 / 430 |
prostate | 98% | 449.86 | 240 / 245 | 17% | 0.29 | 87 / 502 |
kidney | 96% | 191.82 | 85 / 89 | 14% | 0.40 | 123 / 901 |
breast | 92% | 229.32 | 421 / 459 | 13% | 0.25 | 143 / 1118 |
uterus | 88% | 685.29 | 150 / 170 | 13% | 0.63 | 60 / 459 |
spleen | 100% | 262.67 | 241 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 95% | 164.68 | 246 / 258 | 1% | 0.01 | 2 / 230 |
adipose | 96% | 394.63 | 1150 / 1204 | 0% | 0 | 0 / 0 |
bladder | 76% | 114.62 | 16 / 21 | 14% | 0.47 | 73 / 504 |
liver | 81% | 203.16 | 184 / 226 | 2% | 0.03 | 7 / 406 |
stomach | 76% | 94.83 | 274 / 359 | 6% | 0.08 | 16 / 286 |
intestine | 71% | 122.39 | 685 / 966 | 10% | 0.20 | 54 / 527 |
peripheral blood | 78% | 223.67 | 724 / 929 | 0% | 0 | 0 / 0 |
esophagus | 52% | 58.76 | 752 / 1445 | 11% | 0.64 | 20 / 183 |
blood vessel | 55% | 70.35 | 738 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 36% | 38.55 | 118 / 328 | 17% | 0.33 | 30 / 178 |
skin | 50% | 65.53 | 910 / 1809 | 2% | 0.05 | 10 / 472 |
heart | 33% | 39.65 | 287 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 6% | 0.13 | 5 / 80 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
muscle | 2% | 1.99 | 14 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002357 | Biological process | defense response to tumor cell |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0007283 | Biological process | spermatogenesis |
GO_0030154 | Biological process | cell differentiation |
GO_0005929 | Cellular component | cilium |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0048487 | Molecular function | beta-tubulin binding |
GO_0043014 | Molecular function | alpha-tubulin binding |
GO_0005515 | Molecular function | protein binding |
GO_0003674 | Molecular function | molecular_function |
GO_0015631 | Molecular function | tubulin binding |
Gene name | DLEC1 |
Protein name | Deleted in lung and esophageal cancer 1 transcript varient 2 Deleted in lung and esophageal cancer 1 Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1) DLEC1 protein Deleted in lung and esophageal cancer protein 1 Deleted in lung and esophageal cancer 1 transcript variant 1 DLEC1 cilia and flagella associated protein (Deleted in lung and esophageal cancer 1 transcript variant 3) |
Synonyms | DLC1 |
Description | FUNCTION: Essential for spermatogenesis and male fertility (By similarity). May play an important role in sperm head and tail formation (By similarity). May act as a tumor suppressor by inhibiting cell proliferation. . |
Accessions | B7ZW06 Q9Y238 Q32W77 Q32W78 ENST00000346219.7 [Q9Y238-3] ENST00000447130.1 B1B5Y4 ENST00000308059.11 [Q9Y238-1] A2VDF1 A1L305 Q32W76 |