DLEC1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DLEC1 at tissue level.

III. Associated gene sets

GO_0002357Biological processdefense response to tumor cell
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0007283Biological processspermatogenesis
GO_0030154Biological processcell differentiation
GO_0005929Cellular componentcilium
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0048487Molecular functionbeta-tubulin binding
GO_0043014Molecular functionalpha-tubulin binding
GO_0005515Molecular functionprotein binding
GO_0003674Molecular functionmolecular_function
GO_0015631Molecular functiontubulin binding

IV. Literature review

[source]
Gene nameDLEC1
Protein nameDeleted in lung and esophageal cancer 1 transcript varient 2
Deleted in lung and esophageal cancer 1
Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1)
DLEC1 protein
Deleted in lung and esophageal cancer protein 1
Deleted in lung and esophageal cancer 1 transcript variant 1
DLEC1 cilia and flagella associated protein (Deleted in lung and esophageal cancer 1 transcript variant 3)
SynonymsDLC1
DescriptionFUNCTION: Essential for spermatogenesis and male fertility (By similarity). May play an important role in sperm head and tail formation (By similarity). May act as a tumor suppressor by inhibiting cell proliferation. .

AccessionsB7ZW06
Q9Y238
Q32W77
Q32W78
ENST00000346219.7 [Q9Y238-3]
ENST00000447130.1
B1B5Y4
ENST00000308059.11 [Q9Y238-1]
A2VDF1
A1L305
Q32W76