SYT3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SYT3 at tissue level.

III. Associated gene sets

GO_0017156Biological processcalcium-ion regulated exocytosis
GO_1903861Biological processpositive regulation of dendrite extension
GO_0030154Biological processcell differentiation
GO_0070382Cellular componentexocytic vesicle
GO_0030658Cellular componenttransport vesicle membrane
GO_0005768Cellular componentendosome
GO_0005886Cellular componentplasma membrane
GO_0030276Molecular functionclathrin binding
GO_0000149Molecular functionSNARE binding
GO_0005509Molecular functioncalcium ion binding
GO_0005544Molecular functioncalcium-dependent phospholipid binding
GO_0001786Molecular functionphosphatidylserine binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSYT3
Protein nameSynaptotagmin-3 (Synaptotagmin III) (SytIII)
Synaptotagmin 3
Synonyms
DescriptionFUNCTION: Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity). Plays a role in dendrite formation by melanocytes . .

AccessionsM0QYH4
M0QY70
ENST00000338916.8
ENST00000595557.1
Q9BQG1
ENST00000598997.1
ENST00000600079.6
ENST00000593901.5