BTBD18 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of BTBD18 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BTBD18 at tissue level.

III. Associated gene sets

GO_0010526Biological processretrotransposon silencing
GO_0007283Biological processspermatogenesis
GO_0030154Biological processcell differentiation
GO_0140541Biological processpiRNA transcription
GO_0032968Biological processpositive regulation of transcription elongation by RNA polymerase II
GO_0007141Biological processmale meiosis I
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBTBD18
Protein nameBTB/POZ domain-containing protein 18
Synonyms
DescriptionFUNCTION: Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Acts by facilitating transcription elongation at piRNA loci during pachytene. .

AccessionsENST00000436147.3
B2RXH4
E9PRF5
ENST00000527995
ENST00000422652.6
ENST00000527995.2