SEPTIN7 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	44 studies	49% ± 20%	Explore
fibroblast	43 studies	56% ± 20%	Explore
B cell	41 studies	51% ± 17%	Explore
natural killer cell	40 studies	60% ± 20%	Explore
pericyte	39 studies	71% ± 20%	Explore
T cell	38 studies	45% ± 17%	Explore
CD8-positive, alpha-beta T cell	36 studies	51% ± 14%	Explore
smooth muscle cell	34 studies	64% ± 21%	Explore
macrophage	32 studies	37% ± 13%	Explore
CD4-positive, alpha-beta T cell	29 studies	48% ± 16%	Explore
conventional dendritic cell	24 studies	44% ± 13%	Explore
regulatory T cell	24 studies	47% ± 13%	Explore
mast cell	23 studies	43% ± 20%	Explore
endothelial cell of lymphatic vessel	23 studies	50% ± 16%	Explore
astrocyte	21 studies	55% ± 18%	Explore
dendritic cell	20 studies	41% ± 22%	Explore
basal cell	20 studies	42% ± 19%	Explore
epithelial cell	20 studies	38% ± 21%	Explore
non-classical monocyte	19 studies	41% ± 16%	Explore
classical monocyte	19 studies	37% ± 15%	Explore
monocyte	18 studies	34% ± 12%	Explore
mature NK T cell	18 studies	58% ± 16%	Explore
ciliated cell	18 studies	45% ± 18%	Explore
connective tissue cell	18 studies	58% ± 23%	Explore
memory B cell	17 studies	57% ± 11%	Explore
naive B cell	17 studies	52% ± 16%	Explore
gamma-delta T cell	16 studies	63% ± 19%	Explore
plasmacytoid dendritic cell	16 studies	44% ± 16%	Explore
plasma cell	15 studies	32% ± 14%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	15 studies	47% ± 16%	Explore
oligodendrocyte	15 studies	81% ± 12%	Explore
myofibroblast cell	15 studies	61% ± 22%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	63% ± 21%	Explore
mucosal invariant T cell	14 studies	56% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	68% ± 15%	Explore
capillary endothelial cell	14 studies	44% ± 13%	Explore
vein endothelial cell	14 studies	43% ± 13%	Explore
microglial cell	14 studies	38% ± 13%	Explore
oligodendrocyte precursor cell	13 studies	46% ± 19%	Explore
endothelial cell of artery	13 studies	47% ± 14%	Explore
endothelial cell of vascular tree	13 studies	43% ± 16%	Explore
myeloid cell	13 studies	38% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	56% ± 16%	Explore
glutamatergic neuron	12 studies	61% ± 23%	Explore
type I pneumocyte	11 studies	31% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	59% ± 22%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	11 studies	58% ± 17%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	52% ± 10%	Explore
leukocyte	11 studies	47% ± 20%	Explore
GABAergic neuron	11 studies	57% ± 21%	Explore
club cell	10 studies	28% ± 12%	Explore
neuron	10 studies	62% ± 16%	Explore
mesothelial cell	10 studies	57% ± 24%	Explore
platelet	9 studies	44% ± 19%	Explore
alveolar macrophage	8 studies	32% ± 7%	Explore
innate lymphoid cell	8 studies	54% ± 15%	Explore
plasmablast	8 studies	41% ± 20%	Explore
secretory cell	8 studies	34% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	57% ± 22%	Explore
progenitor cell	8 studies	44% ± 21%	Explore
amacrine cell	8 studies	51% ± 23%	Explore
retinal ganglion cell	8 studies	66% ± 31%	Explore
retinal rod cell	8 studies	31% ± 11%	Explore
type II pneumocyte	7 studies	27% ± 11%	Explore
abnormal cell	7 studies	42% ± 13%	Explore
retina horizontal cell	7 studies	87% ± 13%	Explore
hematopoietic stem cell	7 studies	48% ± 15%	Explore
precursor B cell	7 studies	59% ± 14%	Explore
T follicular helper cell	7 studies	43% ± 14%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	56% ± 12%	Explore
mononuclear phagocyte	6 studies	41% ± 13%	Explore
lymphocyte	6 studies	53% ± 17%	Explore
adipocyte	6 studies	25% ± 8%	Explore
cardiac muscle cell	6 studies	24% ± 8%	Explore
glial cell	6 studies	45% ± 23%	Explore
Mueller cell	6 studies	46% ± 18%	Explore
CD4-positive helper T cell	5 studies	46% ± 18%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	57% ± 13%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	55% ± 17%	Explore
hematopoietic precursor cell	5 studies	61% ± 15%	Explore
exhausted T cell	5 studies	61% ± 9%	Explore
ionocyte	5 studies	31% ± 13%	Explore
respiratory goblet cell	5 studies	29% ± 14%	Explore
megakaryocyte	5 studies	57% ± 21%	Explore
retinal bipolar neuron	5 studies	48% ± 22%	Explore
OFF-bipolar cell	5 studies	56% ± 24%	Explore
ON-bipolar cell	5 studies	56% ± 23%	Explore
pro-B cell	5 studies	53% ± 7%	Explore
T-helper 17 cell	5 studies	54% ± 11%	Explore
group 3 innate lymphoid cell	5 studies	68% ± 13%	Explore
immature B cell	5 studies	61% ± 14%	Explore
retinal cone cell	5 studies	42% ± 14%	Explore
adventitial cell	5 studies	54% ± 16%	Explore
double negative thymocyte	5 studies	74% ± 5%	Explore
granulocyte	5 studies	49% ± 14%	Explore
interneuron	5 studies	66% ± 13%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	43% ± 15%	Explore
deuterosomal cell	4 studies	23% ± 2%	Explore
precursor cell	4 studies	56% ± 25%	Explore
GABAergic amacrine cell	4 studies	51% ± 14%	Explore
glycinergic amacrine cell	4 studies	43% ± 11%	Explore
erythroblast	4 studies	48% ± 24%	Explore
muscle cell	4 studies	50% ± 22%	Explore
germinal center B cell	4 studies	46% ± 13%	Explore
intermediate monocyte	4 studies	45% ± 26%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	65% ± 10%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	29% ± 7%	Explore
myoepithelial cell	4 studies	48% ± 26%	Explore
neutrophil	4 studies	27% ± 8%	Explore
enteroendocrine cell	4 studies	38% ± 18%	Explore
goblet cell	4 studies	37% ± 11%	Explore
erythrocyte	4 studies	39% ± 19%	Explore
transit amplifying cell	4 studies	35% ± 22%	Explore
keratinocyte	4 studies	28% ± 8%	Explore
hillock cell	3 studies	23% ± 6%	Explore
pancreatic A cell	3 studies	49% ± 12%	Explore
glomerular endothelial cell	3 studies	45% ± 7%	Explore
kidney loop of Henle epithelial cell	3 studies	23% ± 4%	Explore
podocyte	3 studies	49% ± 20%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	69% ± 20%	Explore
neural crest cell	3 studies	85% ± 7%	Explore
extravillous trophoblast	3 studies	43% ± 11%	Explore
placental villous trophoblast	3 studies	41% ± 5%	Explore
Schwann cell	3 studies	67% ± 15%	Explore
retinal pigment epithelial cell	3 studies	40% ± 16%	Explore
tissue-resident macrophage	3 studies	31% ± 3%	Explore
rod bipolar cell	3 studies	64% ± 10%	Explore
ependymal cell	3 studies	51% ± 22%	Explore
intestinal crypt stem cell	3 studies	24% ± 4%	Explore
chondrocyte	3 studies	43% ± 20%	Explore
melanocyte	3 studies	50% ± 5%	Explore
granule cell	3 studies	47% ± 10%	Explore
double-positive, alpha-beta thymocyte	3 studies	74% ± 8%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	20 studies	44% ± 17%	Explore
brain	18 studies	57% ± 21%	Explore
peripheral blood	15 studies	55% ± 15%	Explore
eye	12 studies	43% ± 15%	Explore
intestine	9 studies	46% ± 19%	Explore
kidney	7 studies	37% ± 13%	Explore
heart	6 studies	32% ± 11%	Explore
bone marrow	5 studies	40% ± 21%	Explore
lymph node	5 studies	47% ± 12%	Explore
liver	5 studies	48% ± 19%	Explore
pancreas	4 studies	34% ± 17%	Explore
uterus	4 studies	65% ± 5%	Explore
breast	4 studies	43% ± 10%	Explore
prostate	4 studies	22% ± 6%	Explore
placenta	3 studies	50% ± 10%	Explore
skin	3 studies	35% ± 3%	Explore
adipose	3 studies	31% ± 5%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	21699.43	2642 / 2642	100%	99.38	705 / 705
esophagus	100%	10036.89	1445 / 1445	100%	30.76	183 / 183
breast	100%	11267.97	459 / 459	100%	36.44	1117 / 1118
lung	100%	9597.25	577 / 578	100%	31.29	1155 / 1155
ovary	100%	11175.52	180 / 180	99%	21.02	427 / 430
thymus	100%	8311.77	651 / 653	99%	28.22	601 / 605
uterus	100%	12327.69	170 / 170	99%	31.47	454 / 459
bladder	100%	10639.95	21 / 21	99%	27.48	498 / 504
prostate	100%	7237.57	244 / 245	99%	21.68	497 / 502
intestine	100%	10790.03	966 / 966	98%	26.05	515 / 527
skin	100%	10867.66	1805 / 1809	98%	48.50	462 / 472
adrenal gland	100%	7312.41	257 / 258	98%	30.89	225 / 230
kidney	97%	5027.83	86 / 89	98%	30.84	881 / 901
stomach	90%	5705.60	323 / 359	97%	25.53	277 / 286
pancreas	49%	1552.61	162 / 328	98%	30.57	175 / 178
liver	54%	1740.75	123 / 226	86%	11.96	350 / 406
blood vessel	100%	18343.40	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	44.43	29 / 29
spleen	100%	8329.20	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	25.80	45 / 45
ureter	0%	0	0 / 0	100%	11.09	1 / 1
adipose	100%	13333.08	1203 / 1204	0%	0	0 / 0
muscle	98%	5274.50	789 / 803	0%	0	0 / 0
heart	97%	7691.75	832 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	86%	16.54	69 / 80
peripheral blood	78%	7571.11	720 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0