CDHR5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032532Biological processregulation of microvillus length
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0007155Biological processcell adhesion
GO_0030154Biological processcell differentiation
GO_0090675Biological processintermicrovillar adhesion
GO_1904970Biological processbrush border assembly
GO_0031526Cellular componentbrush border membrane
GO_0005902Cellular componentmicrovillus
GO_0016324Cellular componentapical plasma membrane
GO_0005905Cellular componentclathrin-coated pit
GO_0070062Cellular componentextracellular exosome
GO_0005886Cellular componentplasma membrane
GO_0031528Cellular componentmicrovillus membrane
GO_0050839Molecular functioncell adhesion molecule binding
GO_0005509Molecular functioncalcium ion binding
GO_0008013Molecular functionbeta-catenin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCDHR5
Protein nameCadherin-related family member 5
Cadherin-related family member 5 (Mu-protocadherin) (Mucin and cadherin-like protein) (Mucin-like protocadherin) (MLPCDH)
Cadherin-related family member 5 (Mucin and cadherin-like, isoform CRA_c)
SynonymsMUPCDH
UNQ2781/PRO7168
hCG_1778294
MUCDHL
DescriptionFUNCTION: Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. .

AccessionsENST00000674088.1 [Q9HBB8-1]
ENST00000531177.5
ENST00000632059.1
E9PLX6
E9PPW2
ENST00000358353.8 [Q9HBB8-4]
E9PKR2
ENST00000631565.1
ENST00000633633.1
ENST00000526077.5
ENST00000349570.11 [Q9HBB8-2]
ENST00000531088.5
ENST00000397542.7 [Q9HBB8-1]
ENST00000534311.1
ENST00000631535.1
Q9HBB8
E9PMY2
ENST00000634167.1
ENST00000619215.2
A0A0G2JMW3
ENST00000617105.3
A0A0G2JP44