DLX4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DLX4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DLX4 at tissue level.

III. Associated gene sets

GO_0009790Biological processembryo development
GO_0030154Biological processcell differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding

IV. Literature review

[source]
Gene nameDLX4
Protein nameHomeobox protein DLX-4 (Beta protein 1) (Homeobox protein DLX-7) (Homeobox protein DLX-8)
SynonymsDLX7
DLX9
DLX8
BP1
DescriptionFUNCTION: May play a role in determining the production of hemoglobin S. May act as a repressor. During embryonic development, plays a role in palatogenesis. .

AccessionsENST00000240306.5 [Q92988-1]
ENST00000411890.3 [Q92988-2]
ENST00000611342.1 [Q92988-3]
Q92988