DLL3 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	7 studies	24% ± 10%	Explore
neuron	3 studies	50% ± 23%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of DLL3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	504.32	2633 / 2642	97%	284.91	682 / 705
skin	17%	14.60	314 / 1809	82%	49.19	387 / 472
ovary	16%	10.88	29 / 180	37%	3.30	158 / 430
eye	0%	0	0 / 0	51%	11.37	41 / 80
lymph node	0%	0	0 / 0	31%	1.49	9 / 29
uterus	1%	0.25	1 / 170	30%	3.24	139 / 459
lung	0%	0.08	1 / 578	18%	4.07	203 / 1155
bladder	0%	0	0 / 21	11%	1.63	57 / 504
peripheral blood	10%	7.53	90 / 929	0%	0	0 / 0
adrenal gland	0%	0	0 / 258	9%	1.11	21 / 230
tonsil	0%	0	0 / 0	9%	1.17	4 / 45
thymus	4%	2.52	27 / 653	4%	0.26	27 / 605
stomach	0%	0	0 / 359	8%	2.13	23 / 286
breast	1%	0.46	4 / 459	7%	0.61	80 / 1118
esophagus	0%	0.05	1 / 1445	8%	0.49	14 / 183
intestine	1%	0.52	8 / 966	6%	0.43	31 / 527
prostate	0%	0	0 / 245	3%	0.17	17 / 502
pancreas	0%	0	0 / 328	3%	0.44	6 / 178
kidney	0%	0	0 / 89	3%	0.19	29 / 901
spleen	2%	0.86	4 / 241	0%	0	0 / 0
liver	0%	0	0 / 226	1%	0.13	5 / 406
adipose	0%	0.15	3 / 1204	0%	0	0 / 0
blood vessel	0%	0.04	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001501	Biological process	skeletal system development
GO_0007386	Biological process	compartment pattern specification
GO_0050768	Biological process	negative regulation of neurogenesis
GO_0045746	Biological process	negative regulation of Notch signaling pathway
GO_0030154	Biological process	cell differentiation
GO_0007219	Biological process	Notch signaling pathway
GO_0001756	Biological process	somitogenesis
GO_0048339	Biological process	paraxial mesoderm development
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005112	Molecular function	Notch binding
GO_0005509	Molecular function	calcium ion binding

Gene name	DLL3
Protein name	Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3) Delta like canonical Notch ligand 3
Synonyms
Description	FUNCTION: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). .
Accessions	M0R177 ENST00000205143.4 [Q9NYJ7-1] ENST00000356433.10 [Q9NYJ7-2] ENST00000596614.5 Q9NYJ7

DLL3 report