TLL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001501Biological processskeletal system development
GO_0030199Biological processcollagen fibril organization
GO_0016485Biological processprotein processing
GO_0030154Biological processcell differentiation
GO_0009953Biological processdorsal/ventral pattern formation
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0004222Molecular functionmetalloendopeptidase activity
GO_0005509Molecular functioncalcium ion binding
GO_0004252Molecular functionserine-type endopeptidase activity
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameTLL1
Protein nameMetalloendopeptidase (EC 3.4.24.-)
Tolloid like 1
Tolloid-like protein 1 (EC 3.4.24.-)
SynonymsTLL
DescriptionFUNCTION: Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.

AccessionsE9PD25
O43897
D6RCE0
ENST00000061240.7 [O43897-1]
ENST00000507499.5
D6RAK5
B7ZLW3
ENST00000504560.5
ENST00000509505.5
ENST00000506144.1
D6RBI6
ENST00000513213.5 [O43897-2]