SOHLH2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SOHLH2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SOHLH2 at tissue level.

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0030154Biological processcell differentiation
GO_0009994Biological processoocyte differentiation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0046982Molecular functionprotein heterodimerization activity
GO_0042803Molecular functionprotein homodimerization activity
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameSOHLH2
Protein nameSpermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2
SynonymsTEB1
DescriptionFUNCTION: Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I (By similarity). .

AccessionsENST00000379881.8 [Q9NX45-1]
Q9NX45
ENST00000317764.6 [Q9NX45-2]