SOHLH1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SOHLH1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SOHLH1 at tissue level.

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0030154Biological processcell differentiation
GO_0009994Biological processoocyte differentiation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding
GO_0042803Molecular functionprotein homodimerization activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameSOHLH1
Protein nameSpermatogenesis and oogenesis specific basic helix-loop-helix 1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
SynonymsTEB2
C9orf157
NOHLH
DescriptionFUNCTION: Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I (By similarity). .

AccessionsA0A669KBI8
ENST00000673731.1
ENST00000298466.9 [Q5JUK2-1]
Q5JUK2
ENST00000425225.2 [Q5JUK2-2]