Insufficient scRNA-seq data for expression of ADAM18 at single-cell level.
Insufficient scRNA-seq data for expression of ADAM18 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 0% | 0 | 0 / 89 | 17% | 1.02 | 155 / 901 |
| breast | 0% | 0.39 | 1 / 459 | 1% | 0.05 | 11 / 1118 |
| esophagus | 0% | 0.08 | 1 / 1445 | 1% | 0.02 | 2 / 183 |
| lung | 0% | 0 | 0 / 578 | 1% | 0.10 | 9 / 1155 |
| stomach | 0% | 0 | 0 / 359 | 1% | 0.01 | 2 / 286 |
| ovary | 0% | 0 | 0 / 180 | 1% | 0.01 | 3 / 430 |
| uterus | 0% | 0 | 0 / 170 | 1% | 0.02 | 3 / 459 |
| peripheral blood | 0% | 0.44 | 3 / 929 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 0% | 0.01 | 1 / 406 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0.00 | 1 / 502 |
| bladder | 0% | 0 | 0 / 21 | 0% | 0.01 | 1 / 504 |
| intestine | 0% | 0 | 0 / 966 | 0% | 0.00 | 1 / 527 |
| thymus | 0% | 0.17 | 1 / 653 | 0% | 0 | 0 / 605 |
| heart | 0% | 0.20 | 1 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| brain | 0% | 0 | 0 / 2642 | 0% | 0 | 0 / 705 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 0% | 0 | 0 / 178 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| skin | 0% | 0 | 0 / 1809 | 0% | 0 | 0 / 472 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008584 | Biological process | male gonad development |
| GO_0007339 | Biological process | binding of sperm to zona pellucida |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0007155 | Biological process | cell adhesion |
| GO_0030154 | Biological process | cell differentiation |
| GO_0006508 | Biological process | proteolysis |
| GO_0016020 | Cellular component | membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004222 | Molecular function | metalloendopeptidase activity |
| GO_0008237 | Molecular function | metallopeptidase activity |
| Gene name | ADAM18 |
| Protein name | Disintegrin and metalloproteinase domain-containing protein 18 (ADAM 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III) (tMDC III) ADAM18 protein ADAM metallopeptidase domain 18 (Disintegrin and metalloproteinase domain-containing protein 18) |
| Synonyms | UNQ858/PRO1867 TMDC3 |
| Description | FUNCTION: Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein (By similarity). . |
| Accessions | ENST00000520001.5 E5RK96 ENST00000520087.5 ENST00000633693.1 Q9Y3Q7 ENST00000614391.2 ENST00000633768.1 [Q9Y3Q7-2] Q0VAI3 ENST00000379866.5 [Q9Y3Q7-2] ENST00000633688.1 [Q9Y3Q7-3] E5RIP0 ENST00000613609.4 [Q9Y3Q7-1] ENST00000265707.10 [Q9Y3Q7-1] ENST00000520772.5 [Q9Y3Q7-3] |