I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 3 studies | 20% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 3 studies | 20% ± 5% |
Insufficient scRNA-seq data for expression of RXRB at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4207.63 | 1445 / 1445 | 100% | 27.65 | 183 / 183 |
| ovary | 100% | 4723.67 | 180 / 180 | 100% | 42.78 | 430 / 430 |
| pancreas | 100% | 2673.96 | 328 / 328 | 100% | 40.33 | 178 / 178 |
| prostate | 100% | 5184.01 | 245 / 245 | 100% | 48.82 | 502 / 502 |
| skin | 100% | 3529.94 | 1809 / 1809 | 100% | 58.04 | 472 / 472 |
| thymus | 100% | 6171.23 | 653 / 653 | 100% | 59.90 | 605 / 605 |
| uterus | 100% | 5389.63 | 170 / 170 | 100% | 49.19 | 459 / 459 |
| lung | 100% | 4251.54 | 578 / 578 | 100% | 42.56 | 1153 / 1155 |
| breast | 100% | 4361.28 | 459 / 459 | 100% | 46.26 | 1116 / 1118 |
| brain | 100% | 3507.22 | 2635 / 2642 | 100% | 67.51 | 705 / 705 |
| stomach | 100% | 3347.50 | 359 / 359 | 100% | 33.09 | 285 / 286 |
| bladder | 100% | 4567.24 | 21 / 21 | 100% | 40.70 | 502 / 504 |
| adrenal gland | 100% | 4110.86 | 258 / 258 | 100% | 45.09 | 229 / 230 |
| intestine | 100% | 4626.99 | 966 / 966 | 99% | 39.42 | 524 / 527 |
| liver | 100% | 2592.18 | 226 / 226 | 99% | 34.96 | 403 / 406 |
| kidney | 100% | 3661.13 | 89 / 89 | 99% | 36.78 | 894 / 901 |
| adipose | 100% | 3936.47 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 55.25 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 46.51 | 29 / 29 |
| muscle | 100% | 3380.25 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5725.90 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 45.23 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.79 | 1 / 1 |
| blood vessel | 100% | 4644.62 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 100% | 2690.90 | 860 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 2896.01 | 908 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0070564 | Biological process | positive regulation of vitamin D receptor signaling pathway |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0030154 | Biological process | cell differentiation |
| GO_0043401 | Biological process | steroid hormone receptor signaling pathway |
| GO_0009755 | Biological process | hormone-mediated signaling pathway |
| GO_0042789 | Biological process | mRNA transcription by RNA polymerase II |
| GO_0032526 | Biological process | response to retinoic acid |
| GO_0048856 | Biological process | anatomical structure development |
| GO_0048384 | Biological process | retinoic acid receptor signaling pathway |
| GO_0030501 | Biological process | positive regulation of bone mineralization |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0003707 | Molecular function | nuclear steroid receptor activity |
| GO_0004879 | Molecular function | nuclear receptor activity |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0044323 | Molecular function | retinoic acid-responsive element binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | RXRB |
| Protein name | Retinoid X receptor, beta Retinoic acid receptor RXR-beta Retinoid X nuclear receptor beta (Retinoid X receptor beta isoform 1) (Retinoid X receptor, beta) Retinoid X receptor beta isoform 3 Retinoic acid receptor RXR-beta (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta) Retinoic acid receptor RXR-beta (Retinoid X receptor beta) Retinoid X receptor beta isoform 4 RXRB (Retinoid X receptor beta isoform 2) |
| Synonyms | NR2B2 RP5-1033B10.6-006 hCG_2042227 RP5-1033B10.6-004 |
| Description | FUNCTION: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE). . |
| Accessions | A0A0G2JKR7 ENST00000383217.8 [P28702-1] ENST00000483281.5 ENST00000462174.5 ENST00000455462.6 [P28702-3] ENST00000451068.1 ENST00000415909.6 [P28702-1] ENST00000383216.8 [P28702-3] ENST00000431820.6 [P28702-1] ENST00000485267.5 ENST00000374680.4 [P28702-1] A0A0S2Z4N9 A0A0S2Z570 ENST00000465169.5 ENST00000468440.5 ENST00000374685.8 [P28702-3] ENST00000415157.6 [P28702-1] Q5STP9 ENST00000463338.5 ENST00000428813.1 A0A0G2JHI1 ENST00000431161.6 [P28702-3] J3JS70 J3JS71 ENST00000443603.6 [P28702-3] ENST00000415668.1 ENST00000436753.6 [P28702-1] P28702 A0A0S2Z4M5 ENST00000441299.1 ENST00000456244.6 [P28702-3] E9PK75 ENST00000531100.5 ENST00000437617.1 |
