Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 9 studies | 27% ± 5% | |
endothelial cell of lymphatic vessel | 8 studies | 20% ± 3% | |
epithelial cell | 6 studies | 32% ± 10% | |
B cell | 5 studies | 21% ± 4% | |
basal cell | 5 studies | 22% ± 8% | |
naive B cell | 4 studies | 16% ± 1% | |
retinal bipolar neuron | 3 studies | 40% ± 12% | |
ciliated cell | 3 studies | 25% ± 10% | |
lymphocyte | 3 studies | 20% ± 2% | |
rod bipolar cell | 3 studies | 21% ± 5% | |
GABAergic neuron | 3 studies | 22% ± 1% | |
glutamatergic neuron | 3 studies | 45% ± 13% | |
oligodendrocyte | 3 studies | 18% ± 1% | |
microglial cell | 3 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 9068.71 | 245 / 245 | 100% | 41.79 | 501 / 502 |
lung | 100% | 4914.70 | 578 / 578 | 99% | 19.31 | 1149 / 1155 |
esophagus | 100% | 3244.28 | 1445 / 1445 | 99% | 26.90 | 182 / 183 |
breast | 100% | 4297.34 | 459 / 459 | 99% | 22.09 | 1109 / 1118 |
uterus | 100% | 4087.46 | 170 / 170 | 98% | 18.80 | 452 / 459 |
pancreas | 100% | 2305.22 | 328 / 328 | 98% | 17.79 | 174 / 178 |
thymus | 100% | 3798.77 | 652 / 653 | 97% | 12.91 | 587 / 605 |
stomach | 100% | 2661.30 | 359 / 359 | 97% | 15.14 | 277 / 286 |
bladder | 100% | 4051.00 | 21 / 21 | 97% | 15.89 | 488 / 504 |
kidney | 100% | 3406.90 | 89 / 89 | 96% | 16.86 | 864 / 901 |
skin | 100% | 5400.92 | 1809 / 1809 | 96% | 18.77 | 451 / 472 |
brain | 98% | 1611.30 | 2578 / 2642 | 98% | 11.37 | 690 / 705 |
intestine | 100% | 3776.69 | 966 / 966 | 95% | 12.34 | 500 / 527 |
liver | 100% | 2400.97 | 226 / 226 | 94% | 14.83 | 383 / 406 |
ovary | 100% | 3296.28 | 180 / 180 | 90% | 8.41 | 386 / 430 |
adrenal gland | 100% | 2168.42 | 258 / 258 | 88% | 7.08 | 202 / 230 |
adipose | 100% | 4532.35 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 23.98 | 29 / 29 |
muscle | 100% | 3037.67 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5131.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 22.76 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.17 | 1 / 1 |
blood vessel | 100% | 3175.21 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 2242.34 | 850 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 84% | 8.90 | 67 / 80 |
peripheral blood | 69% | 2410.44 | 639 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0030154 | Biological process | cell differentiation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003682 | Molecular function | chromatin binding |
Gene name | ELK4 |
Protein name | ETS transcription factor ELK4 ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1) (SRF accessory protein 1) |
Synonyms | SAP1 |
Description | FUNCTION: Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18' (H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously. . |
Accessions | ENST00000357992.9 [P28324-1] ENST00000468523.2 ENST00000289703.8 [P28324-2] P28324 A0A087X2F7 ENST00000616704.4 [P28324-1] |