MGAT4D report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MGAT4D at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MGAT4D at tissue level.

III. Associated gene sets

GO_0006487Biological processprotein N-linked glycosylation
GO_0007283Biological processspermatogenesis
GO_0030154Biological processcell differentiation
GO_0060051Biological processnegative regulation of protein glycosylation
GO_0005795Cellular componentGolgi stack
GO_0000139Cellular componentGolgi membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0008375Molecular functionacetylglucosaminyltransferase activity

IV. Literature review

[source]
Gene nameMGAT4D
Protein nameAlpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D (N-acetylglucosaminyltransferase MGAT1 inhibitory protein) (GlcNAcT-I inhibitory protein) (GnT1IP)
MGAT4 family member D
Synonyms
DescriptionFUNCTION: May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis. .

AccessionsA6NG13
D6RCD2
ENST00000515402.1
ENST00000511113.6
ENST00000515121.5
ENST00000515354.5
D6RIE7
H0Y908
ENST00000513018.5
D6RH02
ENST00000503109.6
D6RCD3