NHLH1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NHLH1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NHLH1 at tissue level.

III. Associated gene sets

GO_0007417Biological processcentral nervous system development
GO_0030154Biological processcell differentiation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameNHLH1
Protein nameNescient helix loop helix 1
Helix-loop-helix protein 1 (HEN-1) (Class A basic helix-loop-helix protein 35) (bHLHa35) (Nescient helix loop helix 1) (NSCL-1)
SynonymsBHLHA35
HEN1
hCG_20859
DescriptionFUNCTION: May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.

AccessionsENST00000302101.6
Q5T203
Q02575