SRA1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
classical monocyte	19 studies	29% ± 9%	Explore
natural killer cell	16 studies	21% ± 4%	Explore
non-classical monocyte	16 studies	26% ± 9%	Explore
monocyte	14 studies	24% ± 8%	Explore
macrophage	14 studies	22% ± 6%	Explore
conventional dendritic cell	11 studies	27% ± 13%	Explore
plasma cell	10 studies	27% ± 11%	Explore
ciliated cell	10 studies	31% ± 13%	Explore
CD8-positive, alpha-beta T cell	10 studies	23% ± 4%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	20% ± 2%	Explore
CD16-positive, CD56-dim natural killer cell, human	9 studies	22% ± 4%	Explore
regulatory T cell	9 studies	22% ± 4%	Explore
endothelial cell	8 studies	23% ± 5%	Explore
epithelial cell	8 studies	33% ± 16%	Explore
plasmacytoid dendritic cell	8 studies	23% ± 7%	Explore
CD4-positive, alpha-beta T cell	7 studies	22% ± 4%	Explore
plasmablast	6 studies	37% ± 22%	Explore
dendritic cell	6 studies	32% ± 17%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	22% ± 5%	Explore
myeloid cell	5 studies	32% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	20% ± 5%	Explore
gamma-delta T cell	5 studies	26% ± 14%	Explore
secretory cell	4 studies	30% ± 17%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	18% ± 1%	Explore
mature NK T cell	4 studies	18% ± 2%	Explore
abnormal cell	4 studies	21% ± 7%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	20% ± 3%	Explore
intermediate monocyte	4 studies	34% ± 11%	Explore
glutamatergic neuron	4 studies	31% ± 10%	Explore
goblet cell	4 studies	20% ± 3%	Explore
basal cell	4 studies	32% ± 17%	Explore
T cell	4 studies	17% ± 2%	Explore
neutrophil	3 studies	19% ± 3%	Explore
leukocyte	3 studies	22% ± 6%	Explore
hematopoietic precursor cell	3 studies	21% ± 2%	Explore
fibroblast	3 studies	27% ± 9%	Explore
exhausted T cell	3 studies	20% ± 6%	Explore
GABAergic neuron	3 studies	30% ± 2%	Explore
B cell	3 studies	19% ± 3%	Explore
mast cell	3 studies	17% ± 1%	Explore
astrocyte	3 studies	18% ± 2%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	23% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	20% ± 4%	Explore
lung	5 studies	27% ± 16%	Explore
brain	5 studies	26% ± 6%	Explore
intestine	3 studies	19% ± 4%	Explore
liver	3 studies	26% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	4972.19	258 / 258	100%	56.70	230 / 230
esophagus	100%	1805.32	1445 / 1445	100%	24.16	183 / 183
kidney	100%	2174.49	89 / 89	100%	32.82	901 / 901
liver	100%	1990.72	226 / 226	100%	38.32	406 / 406
lung	100%	2428.50	578 / 578	100%	32.96	1155 / 1155
ovary	100%	1838.61	180 / 180	100%	38.59	430 / 430
prostate	100%	2384.04	245 / 245	100%	44.92	502 / 502
stomach	100%	2080.79	359 / 359	100%	29.37	286 / 286
thymus	100%	2303.70	653 / 653	100%	46.91	605 / 605
uterus	100%	1563.45	170 / 170	100%	44.74	459 / 459
skin	100%	1741.64	1808 / 1809	100%	39.33	472 / 472
breast	100%	1891.85	459 / 459	100%	36.72	1117 / 1118
intestine	100%	1990.33	966 / 966	100%	32.19	526 / 527
bladder	100%	1761.62	21 / 21	100%	35.48	502 / 504
brain	100%	1989.21	2631 / 2642	100%	44.21	705 / 705
pancreas	99%	928.91	326 / 328	100%	35.17	178 / 178
adipose	100%	1994.46	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	38.80	80 / 80
lymph node	0%	0	0 / 0	100%	60.64	29 / 29
spleen	100%	2436.28	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	44.00	45 / 45
ureter	0%	0	0 / 0	100%	22.02	1 / 1
muscle	100%	2198.16	802 / 803	0%	0	0 / 0
blood vessel	100%	1849.47	1333 / 1335	0%	0	0 / 0
peripheral blood	100%	3580.58	926 / 929	0%	0	0 / 0
heart	98%	1566.95	847 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0045662	Biological process	negative regulation of myoblast differentiation
GO_0071391	Biological process	cellular response to estrogen stimulus
GO_0042981	Biological process	regulation of apoptotic process
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0030154	Biological process	cell differentiation
GO_0007346	Biological process	regulation of mitotic cell cycle
GO_0006915	Biological process	apoptotic process
GO_0005886	Cellular component	plasma membrane
GO_0005654	Cellular component	nucleoplasm
GO_0045171	Cellular component	intercellular bridge
GO_0005829	Cellular component	cytosol
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0005737	Cellular component	cytoplasm
GO_1990904	Cellular component	ribonucleoprotein complex
GO_0031209	Cellular component	SCAR complex
GO_0005634	Cellular component	nucleus
GO_0002153	Molecular function	steroid receptor RNA activator RNA binding
GO_0003713	Molecular function	transcription coactivator activity
GO_0030374	Molecular function	nuclear receptor coactivator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	SRA1
Protein name	Steroid receptor RNA activator 1 Steroid receptor RNA activator 1, isoform CRA_a (cDNA FLJ30398 fis, clone BRACE2008402, highly similar to Steroid receptor RNA activator 1) Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP)
Synonyms	PP7684 hCG_20299
Description	FUNCTION: Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis. .
Accessions	ENST00000336283.9 ENST00000602657.1 B3KNT3 Q9HD15 R4GMW4

SRA1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review