ETS1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	46 studies	41% ± 15%	Explore
natural killer cell	43 studies	46% ± 17%	Explore
CD8-positive, alpha-beta T cell	39 studies	40% ± 15%	Explore
CD4-positive, alpha-beta T cell	36 studies	45% ± 19%	Explore
T cell	34 studies	39% ± 15%	Explore
B cell	30 studies	27% ± 10%	Explore
regulatory T cell	29 studies	48% ± 16%	Explore
pericyte	25 studies	33% ± 16%	Explore
mature NK T cell	22 studies	42% ± 17%	Explore
gamma-delta T cell	19 studies	42% ± 18%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	49% ± 20%	Explore
endothelial cell of lymphatic vessel	17 studies	34% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	17 studies	48% ± 21%	Explore
mucosal invariant T cell	15 studies	44% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	47% ± 19%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	45% ± 17%	Explore
capillary endothelial cell	15 studies	42% ± 12%	Explore
naive B cell	14 studies	30% ± 11%	Explore
endothelial cell of vascular tree	14 studies	35% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	46% ± 20%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	49% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	54% ± 19%	Explore
memory B cell	12 studies	24% ± 11%	Explore
endothelial cell of artery	11 studies	28% ± 9%	Explore
fibroblast	10 studies	22% ± 7%	Explore
innate lymphoid cell	10 studies	43% ± 17%	Explore
vein endothelial cell	10 studies	36% ± 14%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	36% ± 14%	Explore
smooth muscle cell	7 studies	24% ± 5%	Explore
T follicular helper cell	7 studies	42% ± 12%	Explore
CD4-positive helper T cell	6 studies	41% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	32% ± 18%	Explore
plasmacytoid dendritic cell	6 studies	22% ± 4%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	36% ± 15%	Explore
leukocyte	6 studies	41% ± 18%	Explore
lymphocyte	6 studies	55% ± 22%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	54% ± 19%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	43% ± 27%	Explore
exhausted T cell	5 studies	48% ± 19%	Explore
double negative thymocyte	5 studies	50% ± 20%	Explore
platelet	4 studies	21% ± 4%	Explore
endothelial cell of sinusoid	4 studies	36% ± 18%	Explore
glomerular endothelial cell	4 studies	47% ± 7%	Explore
immature B cell	4 studies	22% ± 3%	Explore
oligodendrocyte precursor cell	4 studies	27% ± 9%	Explore
melanocyte	4 studies	32% ± 18%	Explore
plasmablast	3 studies	18% ± 2%	Explore
erythrocyte	3 studies	25% ± 6%	Explore
precursor B cell	3 studies	22% ± 3%	Explore
epithelial cell	3 studies	30% ± 12%	Explore
germinal center B cell	3 studies	25% ± 7%	Explore
basal cell	3 studies	30% ± 13%	Explore
connective tissue cell	3 studies	21% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	54% ± 14%	Explore
T-helper 17 cell	3 studies	48% ± 8%	Explore
T-helper 1 cell	3 studies	46% ± 17%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	51% ± 19%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	29% ± 8%	Explore
mural cell	3 studies	59% ± 16%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	17 studies	31% ± 10%	Explore
lung	7 studies	22% ± 8%	Explore
kidney	3 studies	25% ± 7%	Explore
bone marrow	3 studies	33% ± 10%	Explore
intestine	3 studies	22% ± 4%	Explore
uterus	3 studies	17% ± 2%	Explore
lymph node	3 studies	33% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	9522.33	653 / 653	99%	83.91	600 / 605
breast	100%	14518.74	459 / 459	97%	55.76	1082 / 1118
skin	95%	6163.19	1716 / 1809	99%	105.02	469 / 472
lung	100%	15728.15	578 / 578	94%	46.52	1087 / 1155
kidney	100%	5293.24	89 / 89	89%	102.84	805 / 901
bladder	95%	5435.24	20 / 21	92%	37.45	464 / 504
intestine	99%	5987.31	957 / 966	86%	35.20	455 / 527
uterus	100%	5475.35	170 / 170	85%	30.25	390 / 459
stomach	93%	3440.75	333 / 359	91%	38.91	260 / 286
esophagus	83%	3417.18	1196 / 1445	93%	40.08	171 / 183
prostate	92%	3530.08	225 / 245	80%	22.79	404 / 502
adrenal gland	92%	2952.78	238 / 258	67%	25.09	154 / 230
ovary	99%	3996.14	179 / 180	49%	9.85	212 / 430
pancreas	42%	977.45	137 / 328	98%	68.10	174 / 178
liver	57%	1548.92	129 / 226	63%	16.79	255 / 406
brain	22%	514.34	582 / 2642	93%	38.41	659 / 705
adipose	100%	17783.94	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	211.43	29 / 29
spleen	100%	20269.74	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	13.94	1 / 1
blood vessel	99%	5793.02	1322 / 1335	0%	0	0 / 0
heart	98%	4627.89	842 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	77.65	78 / 80
tonsil	0%	0	0 / 0	91%	45.23	41 / 45
peripheral blood	90%	10654.76	833 / 929	0%	0	0 / 0
muscle	66%	1707.50	527 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0048870	Biological process	cell motility
GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0043536	Biological process	positive regulation of blood vessel endothelial cell migration
GO_0045766	Biological process	positive regulation of angiogenesis
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0010595	Biological process	positive regulation of endothelial cell migration
GO_0010628	Biological process	positive regulation of gene expression
GO_0030578	Biological process	PML body organization
GO_0045765	Biological process	regulation of angiogenesis
GO_0006955	Biological process	immune response
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0030154	Biological process	cell differentiation
GO_1902895	Biological process	positive regulation of miRNA transcription
GO_0045648	Biological process	positive regulation of erythrocyte differentiation
GO_1904996	Biological process	positive regulation of leukocyte adhesion to vascular endothelial cell
GO_0050729	Biological process	positive regulation of inflammatory response
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0003676	Molecular function	nucleic acid binding
GO_0000976	Molecular function	transcription cis-regulatory region binding
GO_0001222	Molecular function	transcription corepressor binding
GO_0042802	Molecular function	identical protein binding
GO_0061629	Molecular function	RNA polymerase II-specific DNA-binding transcription factor binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0030374	Molecular function	nuclear receptor coactivator activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	ETS1
Protein name	ETS proto-oncogene 1, transcription factor ETS1 protein Protein C-ets-1 (p54)
Synonyms	EWSR2
Description	FUNCTION: Transcription factor . Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts . May control the differentiation, survival and proliferation of lymphoid cells . May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion . .; FUNCTION: [Isoform Ets-1 p27]: Acts as a dominant-negative for isoform c-ETS-1A. .
Accessions	ENST00000526145.6 [P14921-2] ENST00000535549.5 [P14921-4] ENST00000531611.5 [P14921-5] ENST00000319397.7 [P14921-1] P14921 ENST00000608978.1 Q6FG54 V9GYD6 ENST00000392668.8 [P14921-3]

ETS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review