SEPTIN12 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of SEPTIN12 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	91%	99.82	2406 / 2642	0%	0	0 / 705
prostate	59%	18.00	144 / 245	2%	0.02	8 / 502
kidney	46%	8.92	41 / 89	0%	0.01	3 / 901
intestine	37%	5.41	357 / 966	0%	0.01	1 / 527
adrenal gland	36%	4.72	93 / 258	0%	0.01	1 / 230
esophagus	35%	5.48	512 / 1445	1%	0.02	1 / 183
breast	33%	9.10	152 / 459	3%	0.04	29 / 1118
ovary	31%	3.57	56 / 180	1%	0.02	5 / 430
spleen	30%	3.44	73 / 241	0%	0	0 / 0
liver	29%	3.86	65 / 226	0%	0	0 / 406
uterus	23%	2.75	39 / 170	1%	0.02	4 / 459
stomach	19%	2.14	67 / 359	1%	0.01	2 / 286
heart	19%	2.52	161 / 861	0%	0	0 / 0
skin	18%	2.89	326 / 1809	0%	0	0 / 472
peripheral blood	15%	1.92	143 / 929	0%	0	0 / 0
thymus	11%	2.68	74 / 653	0%	0.01	3 / 605
lung	11%	1.36	64 / 578	1%	0.01	7 / 1155
muscle	8%	1.91	64 / 803	0%	0	0 / 0
pancreas	7%	0.80	23 / 328	0%	0	0 / 178
adipose	6%	0.87	76 / 1204	0%	0	0 / 0
blood vessel	5%	0.58	65 / 1335	0%	0	0 / 0
bladder	5%	0.67	1 / 21	0%	0	0 / 504
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007283	Biological process	spermatogenesis
GO_0061640	Biological process	cytoskeleton-dependent cytokinesis
GO_0030154	Biological process	cell differentiation
GO_0008104	Biological process	protein localization
GO_0030496	Cellular component	midbody
GO_0032153	Cellular component	cell division site
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0097227	Cellular component	sperm annulus
GO_0001725	Cellular component	stress fiber
GO_0015630	Cellular component	microtubule cytoskeleton
GO_0031105	Cellular component	septin complex
GO_0005940	Cellular component	septin ring
GO_0032154	Cellular component	cleavage furrow
GO_0005819	Cellular component	spindle
GO_0005634	Cellular component	nucleus
GO_0019003	Molecular function	GDP binding
GO_0042803	Molecular function	protein homodimerization activity
GO_0060090	Molecular function	molecular adaptor activity
GO_0042802	Molecular function	identical protein binding
GO_0035091	Molecular function	phosphatidylinositol binding
GO_0005525	Molecular function	GTP binding
GO_0005515	Molecular function	protein binding
GO_0003924	Molecular function	GTPase activity

Gene name	SEPTIN12
Protein name	Septin 12 Alternative protein SEPT12 Septin-12
Synonyms	hCG_15171 SEPT12 FLJ25410
Description	FUNCTION: Filament-forming cytoskeletal GTPase (By similarity). Involved in spermatogenesis. Involved in the morphogenesis of sperm heads and the elongation of sperm tails probably implicating the association with alpha- and beta-tubulins . Forms a filamentous structure with SEPTIN7, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation . May play a role in cytokinesis (Potential). .
Accessions	ENST00000588241.5 K7ES86 L8E6T3 ENST00000590741.5 A0A4P8L6U8 K7EP57 K7EIJ5 Q8IYM1 ENST00000587603.5 ENST00000268231.13 [Q8IYM1-1] K7EP92 ENST00000591624.1 ENST00000396693.9 [Q8IYM1-2]

SEPTIN12 report