ZNF268 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008285Biological processnegative regulation of cell population proliferation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045597Biological processpositive regulation of cell differentiation
GO_0043066Biological processnegative regulation of apoptotic process
GO_0030335Biological processpositive regulation of cell migration
GO_0030154Biological processcell differentiation
GO_0007346Biological processregulation of mitotic cell cycle
GO_0006355Biological processregulation of DNA-templated transcription
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0043065Biological processpositive regulation of apoptotic process
GO_0051726Biological processregulation of cell cycle
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF268
Protein nameZNF268 protein
Zinc finger protein 268 (Zinc finger protein HZF3)
Zinc finger protein 268
Synonyms
DescriptionFUNCTION: [Isoform 1]: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression.; FUNCTION: [Isoform 2]: Contributes to cervical carcinogenesis in part through the TNF-alpha-induced NF-kappa-B signaling pathway by interacting with the I-kappa-B-kinase (IKK) core complex.

FUNCTION: May be involved in transcriptional regulation. .

AccessionsENST00000542711.6
F5H6R9
ENST00000500625.7
K7EQP6
ENST00000541975.2
ENST00000542986.6
K7EIF0
ENST00000228289.9 [Q14587-1]
F5H1T2
F5H7L3
ENST00000592241.5
ENST00000539248.6 [Q14587-6]
F5H670
A0A075B6T9
ENST00000611984.4
F5H467
Q14587
K7EMS6
Q2TB61
ENST00000588312.2 [Q14587-7]
ENST00000541009.6
ENST00000546126.7
ENST00000536899.6
ENST00000591951.1
ENST00000536435.7 [Q14587-1]
A0A087WV54
E7EV44
F5H848
ENST00000541211.6
ENST00000416488.5