Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 8 studies | 23% ± 8% | |
| type I pneumocyte | 7 studies | 31% ± 10% | |
| microglial cell | 6 studies | 25% ± 8% | |
| naive B cell | 5 studies | 18% ± 2% | |
| GABAergic neuron | 5 studies | 28% ± 10% | |
| oligodendrocyte precursor cell | 5 studies | 29% ± 11% | |
| macrophage | 5 studies | 25% ± 6% | |
| oligodendrocyte | 5 studies | 27% ± 5% | |
| B cell | 4 studies | 26% ± 8% | |
| epithelial cell | 4 studies | 46% ± 19% | |
| cardiac muscle cell | 4 studies | 20% ± 3% | |
| glutamatergic neuron | 4 studies | 36% ± 10% | |
| endothelial cell of lymphatic vessel | 4 studies | 19% ± 2% | |
| fibroblast | 4 studies | 18% ± 2% | |
| astrocyte | 4 studies | 29% ± 5% | |
| interneuron | 4 studies | 30% ± 19% | |
| squamous epithelial cell | 3 studies | 49% ± 21% | |
| CD4-positive, alpha-beta T cell | 3 studies | 21% ± 4% | |
| myeloid cell | 3 studies | 18% ± 1% | |
| mast cell | 3 studies | 26% ± 4% | |
| basal cell | 3 studies | 36% ± 27% | |
| club cell | 3 studies | 23% ± 8% | |
| lymphocyte | 3 studies | 21% ± 3% | |
| transit amplifying cell | 3 studies | 38% ± 32% | |
| adipocyte | 3 studies | 21% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 5763.77 | 180 / 180 | 100% | 4.74 | 429 / 430 |
| thymus | 100% | 3523.95 | 653 / 653 | 100% | 12.83 | 603 / 605 |
| prostate | 100% | 1796.79 | 245 / 245 | 100% | 4.81 | 500 / 502 |
| breast | 100% | 1655.19 | 459 / 459 | 99% | 5.87 | 1108 / 1118 |
| esophagus | 100% | 2468.53 | 1444 / 1445 | 99% | 6.09 | 181 / 183 |
| bladder | 100% | 1325.90 | 21 / 21 | 98% | 4.72 | 494 / 504 |
| lung | 100% | 2077.75 | 577 / 578 | 97% | 5.54 | 1125 / 1155 |
| pancreas | 100% | 1153.47 | 327 / 328 | 97% | 3.78 | 173 / 178 |
| intestine | 100% | 1339.75 | 966 / 966 | 96% | 3.32 | 507 / 527 |
| adrenal gland | 100% | 4736.59 | 258 / 258 | 96% | 4.08 | 221 / 230 |
| stomach | 100% | 1071.53 | 358 / 359 | 96% | 3.78 | 274 / 286 |
| brain | 95% | 982.92 | 2514 / 2642 | 100% | 6.02 | 704 / 705 |
| kidney | 100% | 1082.63 | 89 / 89 | 93% | 3.44 | 840 / 901 |
| uterus | 100% | 1902.32 | 170 / 170 | 91% | 4.50 | 416 / 459 |
| skin | 100% | 2023.38 | 1809 / 1809 | 83% | 2.55 | 392 / 472 |
| spleen | 100% | 2211.74 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.65 | 1 / 1 |
| adipose | 100% | 1421.97 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 947.54 | 1322 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 833.16 | 794 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 1006.10 | 842 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 3.60 | 28 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 3.06 | 39 / 45 |
| peripheral blood | 69% | 791.45 | 640 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 48% | 1.13 | 38 / 80 |
| liver | 10% | 41.64 | 23 / 226 | 35% | 0.85 | 141 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030154 | Biological process | cell differentiation |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0043433 | Biological process | negative regulation of DNA-binding transcription factor activity |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | ZNF431 |
| Protein name | Zinc finger protein 431 |
| Synonyms | hCG_1783490 KIAA1969 |
| Description | FUNCTION: Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1 (By similarity). . |
| Accessions | ENST00000594425.5 ENST00000311048.11 M0R1H8 ENST00000600692.5 M0QZN7 Q8TF32 ENST00000599296.5 ENST00000598331.1 M0QZG4 M0QXY3 |