Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 49 studies | 40% ± 12% | |
fibroblast | 39 studies | 29% ± 10% | |
pericyte | 36 studies | 32% ± 13% | |
smooth muscle cell | 34 studies | 38% ± 9% | |
oligodendrocyte | 17 studies | 40% ± 16% | |
astrocyte | 16 studies | 29% ± 12% | |
capillary endothelial cell | 15 studies | 38% ± 7% | |
myofibroblast cell | 14 studies | 34% ± 9% | |
endothelial cell of vascular tree | 14 studies | 44% ± 13% | |
endothelial cell of artery | 13 studies | 44% ± 12% | |
vein endothelial cell | 13 studies | 41% ± 14% | |
connective tissue cell | 11 studies | 31% ± 10% | |
plasma cell | 10 studies | 29% ± 9% | |
mesothelial cell | 10 studies | 32% ± 11% | |
macrophage | 9 studies | 24% ± 10% | |
oligodendrocyte precursor cell | 8 studies | 28% ± 9% | |
epithelial cell of proximal tubule | 7 studies | 33% ± 9% | |
B cell | 6 studies | 21% ± 6% | |
myeloid cell | 6 studies | 27% ± 6% | |
adipocyte | 6 studies | 34% ± 10% | |
cardiac muscle cell | 6 studies | 34% ± 11% | |
monocyte | 5 studies | 26% ± 12% | |
GABAergic neuron | 5 studies | 19% ± 2% | |
epithelial cell | 5 studies | 30% ± 11% | |
retinal rod cell | 5 studies | 24% ± 4% | |
basal cell | 5 studies | 27% ± 7% | |
glomerular endothelial cell | 4 studies | 48% ± 7% | |
naive B cell | 4 studies | 17% ± 1% | |
glial cell | 4 studies | 49% ± 13% | |
neuron | 4 studies | 29% ± 9% | |
type II pneumocyte | 4 studies | 22% ± 6% | |
dendritic cell | 4 studies | 18% ± 2% | |
alveolar macrophage | 4 studies | 26% ± 7% | |
melanocyte | 4 studies | 34% ± 9% | |
plasmablast | 3 studies | 43% ± 18% | |
extravillous trophoblast | 3 studies | 51% ± 25% | |
retinal pigment epithelial cell | 3 studies | 34% ± 7% | |
abnormal cell | 3 studies | 42% ± 12% | |
hepatocyte | 3 studies | 19% ± 3% | |
muscle cell | 3 studies | 60% ± 16% | |
ependymal cell | 3 studies | 32% ± 15% | |
mast cell | 3 studies | 29% ± 9% | |
megakaryocyte | 3 studies | 39% ± 7% | |
adventitial cell | 3 studies | 27% ± 2% | |
chondrocyte | 3 studies | 38% ± 7% | |
Schwann cell | 3 studies | 68% ± 7% | |
myoepithelial cell | 3 studies | 25% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 19046.00 | 458 / 459 | 99% | 198.73 | 1102 / 1118 |
lung | 100% | 24246.06 | 576 / 578 | 97% | 148.59 | 1126 / 1155 |
uterus | 99% | 29591.56 | 168 / 170 | 95% | 159.06 | 437 / 459 |
kidney | 98% | 13757.94 | 87 / 89 | 93% | 426.74 | 837 / 901 |
prostate | 93% | 15389.51 | 229 / 245 | 94% | 112.89 | 470 / 502 |
esophagus | 87% | 23216.42 | 1256 / 1445 | 97% | 164.60 | 178 / 183 |
thymus | 96% | 10349.80 | 624 / 653 | 87% | 71.68 | 529 / 605 |
ovary | 85% | 8698.07 | 153 / 180 | 96% | 112.80 | 413 / 430 |
bladder | 100% | 32905.90 | 21 / 21 | 79% | 94.83 | 399 / 504 |
intestine | 88% | 20347.37 | 850 / 966 | 80% | 82.23 | 423 / 527 |
skin | 71% | 16089.32 | 1283 / 1809 | 94% | 254.45 | 443 / 472 |
stomach | 74% | 13601.56 | 267 / 359 | 84% | 111.34 | 241 / 286 |
adrenal gland | 83% | 6989.46 | 214 / 258 | 73% | 67.18 | 169 / 230 |
brain | 53% | 5332.06 | 1396 / 2642 | 100% | 296.00 | 703 / 705 |
pancreas | 17% | 1048.89 | 57 / 328 | 95% | 131.39 | 169 / 178 |
adipose | 100% | 25466.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 71315.74 | 1335 / 1335 | 0% | 0 | 0 / 0 |
heart | 93% | 18788.68 | 805 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 121.01 | 40 / 45 |
lymph node | 0% | 0 | 0 / 0 | 76% | 72.47 | 22 / 29 |
liver | 23% | 1365.52 | 52 / 226 | 49% | 32.76 | 200 / 406 |
eye | 0% | 0 | 0 / 0 | 71% | 77.76 | 57 / 80 |
spleen | 56% | 4008.82 | 135 / 241 | 0% | 0 | 0 / 0 |
muscle | 24% | 1730.96 | 196 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 18% | 1579.09 | 164 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030216 | Biological process | keratinocyte differentiation |
GO_0001525 | Biological process | angiogenesis |
GO_0006821 | Biological process | chloride transport |
GO_0048754 | Biological process | branching morphogenesis of an epithelial tube |
GO_0061299 | Biological process | retina vasculature morphogenesis in camera-type eye |
GO_0051493 | Biological process | regulation of cytoskeleton organization |
GO_0035264 | Biological process | multicellular organism growth |
GO_0071277 | Biological process | cellular response to calcium ion |
GO_0009566 | Biological process | fertilization |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0030154 | Biological process | cell differentiation |
GO_0007035 | Biological process | vacuolar acidification |
GO_0035088 | Biological process | establishment or maintenance of apical/basal cell polarity |
GO_0030336 | Biological process | negative regulation of cell migration |
GO_0001886 | Biological process | endothelial cell morphogenesis |
GO_0005902 | Cellular component | microvillus |
GO_0030496 | Cellular component | midbody |
GO_0005886 | Cellular component | plasma membrane |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0016020 | Cellular component | membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005813 | Cellular component | centrosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005911 | Cellular component | cell-cell junction |
GO_0016363 | Cellular component | nuclear matrix |
GO_0009986 | Cellular component | cell surface |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0034707 | Cellular component | chloride channel complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0045177 | Cellular component | apical part of cell |
GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
GO_0005515 | Molecular function | protein binding |
GO_0005254 | Molecular function | chloride channel activity |
Gene name | CLIC4 |
Protein name | Chloride intracellular channel protein 4 (Intracellular chloride ion channel protein p64H1) Chloride intracellular channel protein |
Synonyms | hCG_24047 |
Description | FUNCTION: Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis). . |
Accessions | ENST00000374379.9 Q9Y696 Q6FIC5 ENST00000488683.1 |