I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 23% ± 5% | |
| GABAergic neuron | 3 studies | 28% ± 12% | |
| glutamatergic neuron | 3 studies | 34% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 23% ± 5% | |
| GABAergic neuron | 3 studies | 28% ± 12% | |
| glutamatergic neuron | 3 studies | 34% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 21% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 3771.91 | 180 / 180 | 97% | 51.57 | 417 / 430 |
| pancreas | 99% | 1886.97 | 325 / 328 | 94% | 38.70 | 167 / 178 |
| prostate | 100% | 4529.44 | 245 / 245 | 90% | 20.41 | 451 / 502 |
| uterus | 100% | 4665.27 | 170 / 170 | 88% | 40.53 | 402 / 459 |
| breast | 100% | 2259.34 | 459 / 459 | 85% | 26.42 | 950 / 1118 |
| thymus | 100% | 1695.90 | 650 / 653 | 85% | 27.74 | 515 / 605 |
| lung | 100% | 3191.45 | 578 / 578 | 84% | 32.97 | 972 / 1155 |
| bladder | 100% | 3742.38 | 21 / 21 | 78% | 40.70 | 395 / 504 |
| esophagus | 99% | 1518.22 | 1431 / 1445 | 77% | 23.78 | 141 / 183 |
| kidney | 99% | 1268.28 | 88 / 89 | 75% | 23.80 | 677 / 901 |
| liver | 98% | 1457.91 | 222 / 226 | 57% | 10.58 | 230 / 406 |
| stomach | 98% | 1429.40 | 353 / 359 | 55% | 16.19 | 156 / 286 |
| skin | 100% | 2524.92 | 1809 / 1809 | 46% | 22.89 | 219 / 472 |
| brain | 95% | 2027.69 | 2504 / 2642 | 51% | 8.15 | 360 / 705 |
| intestine | 84% | 1141.89 | 815 / 966 | 46% | 13.79 | 243 / 527 |
| adrenal gland | 59% | 519.40 | 153 / 258 | 65% | 15.57 | 149 / 230 |
| muscle | 100% | 2852.54 | 803 / 803 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 36.46 | 1 / 1 |
| adipose | 100% | 1896.51 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2132.58 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 94% | 1684.48 | 813 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 83% | 28.65 | 66 / 80 |
| spleen | 81% | 620.72 | 196 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 67% | 17.05 | 30 / 45 |
| peripheral blood | 0% | 3.82 | 4 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0034109 | Biological process | homotypic cell-cell adhesion |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0007185 | Biological process | cell surface receptor protein tyrosine phosphatase signaling pathway |
| GO_0051384 | Biological process | response to glucocorticoid |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0031100 | Biological process | animal organ regeneration |
| GO_0007155 | Biological process | cell adhesion |
| GO_0030154 | Biological process | cell differentiation |
| GO_0034394 | Biological process | protein localization to cell surface |
| GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
| GO_2000049 | Biological process | positive regulation of cell-cell adhesion mediated by cadherin |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005001 | Molecular function | transmembrane receptor protein tyrosine phosphatase activity |
| GO_0008013 | Molecular function | beta-catenin binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
| Gene name | PTPRU |
| Protein name | Alternative protein PTPRU Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi) |
| Synonyms | PCP2 FMI PTPRO |
| Description | FUNCTION: Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis. . |
| Accessions | ENST00000345512.7 [Q92729-1] ENST00000373779.8 [Q92729-2] ENST00000428026.6 [Q92729-3] ENST00000460170.2 [Q92729-4] L8ECC6 Q92729 |
