Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 19 studies | 40% ± 15% | |
| ciliated cell | 17 studies | 37% ± 16% | |
| epithelial cell | 12 studies | 40% ± 20% | |
| club cell | 10 studies | 39% ± 16% | |
| secretory cell | 9 studies | 38% ± 12% | |
| type II pneumocyte | 8 studies | 25% ± 8% | |
| respiratory goblet cell | 8 studies | 44% ± 23% | |
| brush cell | 5 studies | 44% ± 12% | |
| goblet cell | 5 studies | 41% ± 18% | |
| deuterosomal cell | 4 studies | 25% ± 9% | |
| duct epithelial cell | 4 studies | 58% ± 20% | |
| squamous epithelial cell | 4 studies | 56% ± 13% | |
| mucus secreting cell | 4 studies | 47% ± 24% | |
| hillock cell | 3 studies | 32% ± 18% | |
| serous secreting cell | 3 studies | 39% ± 15% | |
| keratinocyte | 3 studies | 27% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 93% | 5570.06 | 227 / 245 | 100% | 215.09 | 502 / 502 |
| pancreas | 97% | 1445.00 | 317 / 328 | 93% | 96.45 | 166 / 178 |
| stomach | 73% | 1873.09 | 261 / 359 | 94% | 130.39 | 269 / 286 |
| lung | 58% | 1007.67 | 337 / 578 | 90% | 91.15 | 1038 / 1155 |
| intestine | 47% | 2195.31 | 455 / 966 | 97% | 145.85 | 510 / 527 |
| breast | 59% | 2474.52 | 270 / 459 | 82% | 121.46 | 914 / 1118 |
| bladder | 48% | 1940.24 | 10 / 21 | 92% | 131.07 | 462 / 504 |
| esophagus | 40% | 6534.70 | 575 / 1445 | 92% | 129.47 | 168 / 183 |
| ureter | 0% | 0 | 0 / 0 | 100% | 27.82 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 183.22 | 43 / 45 |
| ovary | 2% | 11.22 | 4 / 180 | 90% | 92.26 | 388 / 430 |
| uterus | 11% | 348.91 | 18 / 170 | 77% | 138.60 | 355 / 459 |
| skin | 72% | 2790.75 | 1305 / 1809 | 4% | 1.79 | 17 / 472 |
| kidney | 57% | 661.30 | 51 / 89 | 6% | 3.19 | 51 / 901 |
| thymus | 3% | 22.04 | 19 / 653 | 28% | 13.01 | 171 / 605 |
| liver | 0% | 0 | 0 / 226 | 22% | 15.72 | 90 / 406 |
| adrenal gland | 1% | 11.93 | 3 / 258 | 1% | 0.22 | 2 / 230 |
| adipose | 2% | 33.08 | 20 / 1204 | 0% | 0 | 0 / 0 |
| brain | 2% | 11.58 | 42 / 2642 | 0% | 0 | 0 / 705 |
| muscle | 0% | 3.73 | 2 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 1.57 | 2 / 1335 | 0% | 0 | 0 / 0 |
| heart | 0% | 1.08 | 1 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 2.11 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0030154 | Biological process | cell differentiation |
| GO_0030855 | Biological process | epithelial cell differentiation |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Gene name | EHF |
| Protein name | ETS homologous factor (hEHF) (ETS domain-containing transcription factor) (Epithelium-specific Ets transcription factor 3) (ESE-3) ETS homologous factor |
| Synonyms | ESE3 ESE3B ESEJ |
| Description | FUNCTION: Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter. May contribute to development and carcinogenesis by acting as a tumor suppressor gene or anti-oncogene. . |
| Accessions | ENST00000532302.1 ENST00000531794.5 [Q9NZC4-3] ENST00000531728.5 Q9NZC4 ENST00000529527.5 ENST00000525253.5 E9PN75 ENST00000533754.5 [Q9NZC4-1] E9PPS9 ENST00000257831.8 [Q9NZC4-1] ENST00000527935.1 ENST00000450654.6 [Q9NZC4-2] ENST00000530286.5 [Q9NZC4-1] E9PQR6 E9PQX0 |