MOSMO report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045664Biological processregulation of neuron differentiation
GO_0045879Biological processnegative regulation of smoothened signaling pathway
GO_0030154Biological processcell differentiation
GO_0031647Biological processregulation of protein stability
GO_0060170Cellular componentciliary membrane
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane

IV. Literature review

[source]
Gene nameMOSMO
Protein nameModulator of smoothened
Modulator of smoothened protein (Attenuator of hedgehog)
SynonymsC16orf52
ATTHOG
DescriptionFUNCTION: Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane. Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation. .

AccessionsH3BP60
ENST00000562186.1
A0A075B731
ENST00000562695.1
ENST00000567004.1
ENST00000569656.5
ENST00000331057.8 [Q8NHV5-3]
H3BQB3
Q8NHV5
ENST00000542527.7 [Q8NHV5-1]
H3BS23