Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 14 studies | 26% ± 10% | |
fibroblast | 8 studies | 20% ± 3% | |
glutamatergic neuron | 7 studies | 51% ± 20% | |
astrocyte | 7 studies | 29% ± 12% | |
oligodendrocyte | 6 studies | 27% ± 7% | |
neuron | 5 studies | 28% ± 11% | |
endothelial cell of lymphatic vessel | 5 studies | 21% ± 2% | |
oligodendrocyte precursor cell | 5 studies | 31% ± 12% | |
macrophage | 5 studies | 21% ± 5% | |
GABAergic neuron | 5 studies | 44% ± 16% | |
epithelial cell | 4 studies | 26% ± 6% | |
retina horizontal cell | 4 studies | 19% ± 4% | |
interneuron | 4 studies | 54% ± 21% | |
ciliated cell | 3 studies | 17% ± 0% | |
pericyte | 3 studies | 19% ± 2% | |
basal cell | 3 studies | 24% ± 7% | |
smooth muscle cell | 3 studies | 16% ± 1% | |
granule cell | 3 studies | 24% ± 5% | |
microglial cell | 3 studies | 25% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1609.91 | 2635 / 2642 | 100% | 10.94 | 705 / 705 |
breast | 100% | 1368.46 | 459 / 459 | 99% | 8.84 | 1112 / 1118 |
lung | 100% | 1550.98 | 577 / 578 | 100% | 6.62 | 1150 / 1155 |
prostate | 100% | 1708.63 | 245 / 245 | 99% | 7.55 | 497 / 502 |
adrenal gland | 100% | 1878.57 | 258 / 258 | 99% | 10.21 | 227 / 230 |
esophagus | 100% | 1124.25 | 1445 / 1445 | 98% | 6.93 | 180 / 183 |
kidney | 100% | 931.54 | 89 / 89 | 98% | 7.56 | 879 / 901 |
thymus | 100% | 1274.40 | 653 / 653 | 98% | 6.40 | 590 / 605 |
pancreas | 99% | 584.96 | 324 / 328 | 98% | 7.34 | 175 / 178 |
ovary | 100% | 1799.89 | 180 / 180 | 97% | 4.81 | 416 / 430 |
uterus | 100% | 1748.48 | 170 / 170 | 97% | 6.18 | 443 / 459 |
bladder | 100% | 1366.71 | 21 / 21 | 96% | 5.39 | 486 / 504 |
stomach | 100% | 933.21 | 359 / 359 | 94% | 5.10 | 269 / 286 |
skin | 100% | 1485.96 | 1805 / 1809 | 93% | 11.11 | 441 / 472 |
intestine | 100% | 1142.62 | 966 / 966 | 93% | 4.76 | 491 / 527 |
liver | 100% | 686.99 | 226 / 226 | 90% | 4.49 | 364 / 406 |
adipose | 100% | 1486.42 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1076.32 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.51 | 1 / 1 |
blood vessel | 100% | 1124.13 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 868.78 | 801 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 777.17 | 854 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 4.44 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 86% | 3.79 | 25 / 29 |
eye | 0% | 0 | 0 / 0 | 63% | 3.31 | 50 / 80 |
peripheral blood | 41% | 220.73 | 380 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045664 | Biological process | regulation of neuron differentiation |
GO_0045879 | Biological process | negative regulation of smoothened signaling pathway |
GO_0030154 | Biological process | cell differentiation |
GO_0031647 | Biological process | regulation of protein stability |
GO_0060170 | Cellular component | ciliary membrane |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005886 | Cellular component | plasma membrane |
Gene name | MOSMO |
Protein name | Modulator of smoothened Modulator of smoothened protein (Attenuator of hedgehog) |
Synonyms | C16orf52 ATTHOG |
Description | FUNCTION: Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane. Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation. . |
Accessions | H3BP60 ENST00000562186.1 A0A075B731 ENST00000562695.1 ENST00000567004.1 ENST00000569656.5 ENST00000331057.8 [Q8NHV5-3] H3BQB3 Q8NHV5 ENST00000542527.7 [Q8NHV5-1] H3BS23 |