SLFN5 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	37 studies	29% ± 9%	Explore
CD8-positive, alpha-beta T cell	31 studies	27% ± 10%	Explore
T cell	26 studies	26% ± 8%	Explore
CD4-positive, alpha-beta T cell	25 studies	28% ± 9%	Explore
regulatory T cell	24 studies	31% ± 9%	Explore
endothelial cell	23 studies	27% ± 9%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	28% ± 9%	Explore
gamma-delta T cell	17 studies	31% ± 11%	Explore
ciliated cell	16 studies	29% ± 12%	Explore
mature NK T cell	16 studies	29% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	15 studies	31% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	15 studies	32% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	30% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	13 studies	31% ± 9%	Explore
mucosal invariant T cell	13 studies	24% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	11 studies	31% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	29% ± 9%	Explore
endothelial cell of artery	10 studies	22% ± 6%	Explore
secretory cell	7 studies	23% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	30% ± 6%	Explore
basal cell	7 studies	25% ± 8%	Explore
vein endothelial cell	7 studies	20% ± 4%	Explore
T follicular helper cell	7 studies	23% ± 5%	Explore
capillary endothelial cell	6 studies	21% ± 4%	Explore
endothelial cell of vascular tree	6 studies	20% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	32% ± 4%	Explore
exhausted T cell	5 studies	37% ± 10%	Explore
innate lymphoid cell	5 studies	31% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	24% ± 5%	Explore
fibroblast	4 studies	24% ± 5%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	27% ± 8%	Explore
respiratory goblet cell	4 studies	25% ± 7%	Explore
epithelial cell	4 studies	43% ± 24%	Explore
lymphocyte	4 studies	33% ± 9%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	40% ± 3%	Explore
CD4-positive helper T cell	4 studies	22% ± 3%	Explore
mast cell	4 studies	25% ± 13%	Explore
double negative thymocyte	4 studies	34% ± 9%	Explore
leukocyte	3 studies	30% ± 11%	Explore
non-classical monocyte	3 studies	21% ± 6%	Explore
club cell	3 studies	28% ± 13%	Explore
T-helper 17 cell	3 studies	23% ± 3%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	31% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	22% ± 4%	Explore
lung	5 studies	30% ± 9%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	5725.37	578 / 578	98%	33.24	1136 / 1155
esophagus	99%	2734.00	1437 / 1445	98%	28.81	180 / 183
thymus	100%	2325.62	651 / 653	97%	21.64	586 / 605
breast	100%	4204.59	459 / 459	94%	26.54	1049 / 1118
prostate	100%	3057.95	245 / 245	92%	16.05	463 / 502
uterus	99%	2637.00	169 / 170	90%	23.33	415 / 459
skin	94%	3675.09	1698 / 1809	91%	21.88	430 / 472
bladder	100%	3651.43	21 / 21	82%	18.40	412 / 504
ovary	83%	1115.04	150 / 180	95%	18.40	407 / 430
kidney	90%	1428.53	80 / 89	88%	20.02	790 / 901
stomach	97%	1966.08	350 / 359	78%	14.71	222 / 286
intestine	98%	2558.60	947 / 966	76%	12.04	398 / 527
pancreas	62%	679.42	204 / 328	93%	20.40	166 / 178
adrenal gland	97%	3452.35	251 / 258	46%	4.90	106 / 230
adipose	100%	4840.98	1204 / 1204	0%	0	0 / 0
spleen	100%	4692.98	241 / 241	0%	0	0 / 0
blood vessel	99%	2335.13	1327 / 1335	0%	0	0 / 0
muscle	99%	4956.60	791 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	40.38	43 / 45
heart	93%	1340.46	797 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	83%	21.34	24 / 29
brain	32%	328.60	835 / 2642	50%	4.82	352 / 705
peripheral blood	72%	2254.03	666 / 929	0%	0	0 / 0
liver	31%	281.14	70 / 226	33%	3.65	132 / 406
eye	0%	0	0 / 0	44%	3.89	35 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1