NKX6-3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NKX6-3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NKX6-3 at tissue level.

III. Associated gene sets

GO_0030857Biological processnegative regulation of epithelial cell differentiation
GO_0035883Biological processenteroendocrine cell differentiation
GO_0030154Biological processcell differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0001709Biological processcell fate determination
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding

IV. Literature review

[source]
Gene nameNKX6-3
Protein nameHomeobox protein Nkx-6.3
Synonyms
DescriptionFUNCTION: Putative transcription factor, which may be involved in patterning of central nervous system and pancreas. .

AccessionsENST00000524115.2 [A6NJ46-2]
ENST00000518699.4 [A6NJ46-1]
A6NJ46