Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 9 studies | 31% ± 11% | |
| retinal cone cell | 8 studies | 75% ± 14% | |
| retinal rod cell | 8 studies | 66% ± 22% | |
| astrocyte | 8 studies | 32% ± 8% | |
| GABAergic neuron | 6 studies | 39% ± 14% | |
| glutamatergic neuron | 6 studies | 45% ± 20% | |
| adipocyte | 5 studies | 19% ± 3% | |
| oligodendrocyte precursor cell | 5 studies | 27% ± 7% | |
| endothelial cell | 4 studies | 21% ± 6% | |
| interneuron | 4 studies | 46% ± 12% | |
| epithelial cell | 3 studies | 19% ± 2% | |
| retina horizontal cell | 3 studies | 39% ± 9% | |
| oligodendrocyte | 3 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 53.13 | 180 / 180 | 73% | 2.34 | 312 / 430 |
| prostate | 99% | 68.27 | 242 / 245 | 62% | 1.70 | 311 / 502 |
| breast | 98% | 75.33 | 451 / 459 | 54% | 1.85 | 608 / 1118 |
| lung | 99% | 151.61 | 575 / 578 | 46% | 1.33 | 533 / 1155 |
| esophagus | 82% | 28.98 | 1192 / 1445 | 56% | 1.26 | 102 / 183 |
| uterus | 97% | 67.32 | 165 / 170 | 29% | 1.13 | 135 / 459 |
| thymus | 100% | 75.73 | 651 / 653 | 22% | 0.36 | 132 / 605 |
| stomach | 87% | 33.80 | 311 / 359 | 32% | 0.91 | 91 / 286 |
| bladder | 100% | 32.76 | 21 / 21 | 15% | 0.58 | 77 / 504 |
| kidney | 92% | 38.01 | 82 / 89 | 17% | 0.41 | 154 / 901 |
| intestine | 89% | 30.78 | 864 / 966 | 17% | 0.46 | 88 / 527 |
| spleen | 100% | 162.36 | 241 / 241 | 0% | 0 | 0 / 0 |
| pancreas | 80% | 29.28 | 264 / 328 | 17% | 0.49 | 31 / 178 |
| peripheral blood | 98% | 568.83 | 908 / 929 | 0% | 0 | 0 / 0 |
| adipose | 98% | 57.87 | 1175 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 96% | 38.78 | 247 / 258 | 1% | 0.01 | 2 / 230 |
| skin | 84% | 31.24 | 1520 / 1809 | 9% | 0.14 | 42 / 472 |
| brain | 69% | 45.37 | 1823 / 2642 | 23% | 0.68 | 159 / 705 |
| blood vessel | 86% | 30.96 | 1154 / 1335 | 0% | 0 | 0 / 0 |
| heart | 64% | 19.18 | 554 / 861 | 0% | 0 | 0 / 0 |
| liver | 41% | 9.24 | 92 / 226 | 4% | 0.05 | 16 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 0.59 | 11 / 45 |
| muscle | 23% | 5.10 | 183 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.23 | 3 / 29 |
| eye | 0% | 0 | 0 / 0 | 8% | 0.95 | 6 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1905515 | Biological process | non-motile cilium assembly |
| GO_0060271 | Biological process | cilium assembly |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0045494 | Biological process | photoreceptor cell maintenance |
| GO_1902856 | Biological process | negative regulation of non-motile cilium assembly |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0030154 | Biological process | cell differentiation |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0046777 | Biological process | protein autophosphorylation |
| GO_0042073 | Biological process | intraciliary transport |
| GO_0030496 | Cellular component | midbody |
| GO_0032391 | Cellular component | photoreceptor connecting cilium |
| GO_0001750 | Cellular component | photoreceptor outer segment |
| GO_0072686 | Cellular component | mitotic spindle |
| GO_0005813 | Cellular component | centrosome |
| GO_0031514 | Cellular component | motile cilium |
| GO_0001917 | Cellular component | photoreceptor inner segment |
| GO_0005930 | Cellular component | axoneme |
| GO_0005929 | Cellular component | cilium |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0004674 | Molecular function | protein serine/threonine kinase activity |
| GO_0004672 | Molecular function | protein kinase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003713 | Molecular function | transcription coactivator activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MAK |
| Protein name | MAK protein (Male germ cell associated kinase) Male germ cell associated kinase Male germ cell-associated kinase retina-specific isoform Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase) |
| Synonyms | |
| Description | FUNCTION: Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells. . |
| Accessions | ENST00000313243.6 [P20794-1] F8VBW7 P20794 ENST00000536370.6 [P20794-3] A0A6Q8PH30 ENST00000474039.5 [P20794-1] A0A6Q8PG01 Q8IXN4 ENST00000675026.1 ENST00000676116.1 ENST00000538030.3 ENST00000354489.7 [P20794-2] |