ELF1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	45 studies	35% ± 12%	Explore
B cell	41 studies	43% ± 11%	Explore
natural killer cell	38 studies	41% ± 12%	Explore
T cell	35 studies	39% ± 13%	Explore
macrophage	35 studies	39% ± 17%	Explore
CD8-positive, alpha-beta T cell	35 studies	39% ± 12%	Explore
CD4-positive, alpha-beta T cell	31 studies	44% ± 13%	Explore
mast cell	28 studies	54% ± 17%	Explore
regulatory T cell	27 studies	45% ± 15%	Explore
classical monocyte	24 studies	36% ± 10%	Explore
conventional dendritic cell	22 studies	33% ± 14%	Explore
non-classical monocyte	22 studies	41% ± 13%	Explore
mature NK T cell	21 studies	39% ± 12%	Explore
monocyte	20 studies	40% ± 16%	Explore
fibroblast	20 studies	29% ± 10%	Explore
memory B cell	20 studies	44% ± 14%	Explore
endothelial cell of lymphatic vessel	19 studies	33% ± 11%	Explore
naive B cell	19 studies	43% ± 13%	Explore
dendritic cell	17 studies	40% ± 17%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	17 studies	38% ± 11%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	40% ± 12%	Explore
basal cell	16 studies	31% ± 17%	Explore
gamma-delta T cell	16 studies	48% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	43% ± 11%	Explore
ciliated cell	15 studies	33% ± 14%	Explore
plasmacytoid dendritic cell	14 studies	28% ± 8%	Explore
capillary endothelial cell	14 studies	25% ± 5%	Explore
oligodendrocyte	14 studies	31% ± 11%	Explore
microglial cell	14 studies	43% ± 16%	Explore
mucosal invariant T cell	14 studies	41% ± 10%	Explore
plasma cell	13 studies	32% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	39% ± 11%	Explore
endothelial cell of vascular tree	13 studies	35% ± 12%	Explore
myeloid cell	13 studies	43% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	44% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	48% ± 15%	Explore
endothelial cell of artery	12 studies	32% ± 9%	Explore
epithelial cell	12 studies	39% ± 21%	Explore
platelet	11 studies	28% ± 7%	Explore
leukocyte	11 studies	44% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell	11 studies	47% ± 13%	Explore
vein endothelial cell	11 studies	30% ± 17%	Explore
pericyte	10 studies	24% ± 7%	Explore
astrocyte	10 studies	29% ± 13%	Explore
adipocyte	9 studies	38% ± 16%	Explore
alveolar macrophage	8 studies	34% ± 18%	Explore
type I pneumocyte	8 studies	32% ± 10%	Explore
neutrophil	8 studies	30% ± 13%	Explore
oligodendrocyte precursor cell	8 studies	26% ± 9%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	33% ± 7%	Explore
mononuclear phagocyte	7 studies	42% ± 14%	Explore
hematopoietic stem cell	7 studies	52% ± 13%	Explore
innate lymphoid cell	7 studies	42% ± 10%	Explore
club cell	7 studies	31% ± 8%	Explore
secretory cell	7 studies	26% ± 10%	Explore
T follicular helper cell	7 studies	53% ± 15%	Explore
smooth muscle cell	6 studies	23% ± 9%	Explore
plasmablast	6 studies	46% ± 21%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	40% ± 10%	Explore
lymphocyte	6 studies	47% ± 18%	Explore
precursor B cell	6 studies	50% ± 12%	Explore
immature B cell	6 studies	42% ± 2%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	44% ± 17%	Explore
type II pneumocyte	6 studies	33% ± 6%	Explore
CD4-positive helper T cell	5 studies	39% ± 20%	Explore
hematopoietic precursor cell	5 studies	53% ± 19%	Explore
exhausted T cell	5 studies	41% ± 13%	Explore
pro-B cell	5 studies	44% ± 7%	Explore
cardiac muscle cell	5 studies	45% ± 13%	Explore
respiratory goblet cell	5 studies	32% ± 12%	Explore
abnormal cell	5 studies	30% ± 15%	Explore
granulocyte	5 studies	54% ± 20%	Explore
goblet cell	5 studies	36% ± 27%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	39% ± 7%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	33% ± 13%	Explore
megakaryocyte	4 studies	53% ± 20%	Explore
myofibroblast cell	4 studies	23% ± 6%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	26% ± 8%	Explore
luminal cell of prostate epithelium	4 studies	27% ± 7%	Explore
connective tissue cell	4 studies	24% ± 7%	Explore
double negative thymocyte	4 studies	56% ± 10%	Explore
ionocyte	3 studies	34% ± 9%	Explore
pancreatic A cell	3 studies	24% ± 5%	Explore
glomerular endothelial cell	3 studies	23% ± 2%	Explore
squamous epithelial cell	3 studies	40% ± 24%	Explore
brush cell	3 studies	38% ± 8%	Explore
glial cell	3 studies	19% ± 3%	Explore
mesothelial cell	3 studies	28% ± 9%	Explore
tissue-resident macrophage	3 studies	45% ± 14%	Explore
germinal center B cell	3 studies	41% ± 8%	Explore
intermediate monocyte	3 studies	59% ± 16%	Explore
hepatocyte	3 studies	50% ± 18%	Explore
muscle cell	3 studies	21% ± 6%	Explore
glutamatergic neuron	3 studies	19% ± 2%	Explore
pancreatic ductal cell	3 studies	37% ± 15%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	76% ± 12%	Explore
enteroendocrine cell	3 studies	23% ± 4%	Explore
intestinal crypt stem cell	3 studies	19% ± 2%	Explore
adventitial cell	3 studies	22% ± 6%	Explore
group 3 innate lymphoid cell	3 studies	59% ± 11%	Explore
keratinocyte	3 studies	24% ± 7%	Explore
T-helper 17 cell	3 studies	45% ± 14%	Explore
T-helper 1 cell	3 studies	45% ± 19%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	44% ± 6%	Explore
double-positive, alpha-beta thymocyte	3 studies	60% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	26% ± 7%	Explore
mural cell	3 studies	41% ± 18%	Explore
mucus secreting cell	3 studies	30% ± 5%	Explore
erythrocyte	3 studies	35% ± 7%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	18 studies	32% ± 11%	Explore
peripheral blood	17 studies	40% ± 13%	Explore
brain	11 studies	25% ± 10%	Explore
intestine	8 studies	25% ± 8%	Explore
kidney	6 studies	28% ± 10%	Explore
heart	5 studies	37% ± 11%	Explore
breast	5 studies	24% ± 7%	Explore
liver	5 studies	41% ± 10%	Explore
bone marrow	4 studies	38% ± 12%	Explore
uterus	4 studies	31% ± 6%	Explore
lymph node	4 studies	38% ± 16%	Explore
prostate	4 studies	24% ± 7%	Explore
adipose	4 studies	35% ± 9%	Explore
placenta	3 studies	27% ± 13%	Explore
skin	3 studies	21% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3883.14	1445 / 1445	100%	84.40	183 / 183
lung	100%	5213.78	578 / 578	100%	58.51	1153 / 1155
stomach	100%	2719.17	359 / 359	100%	78.17	285 / 286
intestine	100%	4198.40	966 / 966	100%	78.06	525 / 527
breast	100%	5406.90	459 / 459	99%	76.60	1105 / 1118
thymus	100%	4694.84	653 / 653	99%	74.48	596 / 605
pancreas	100%	2374.57	327 / 328	98%	62.74	175 / 178
ovary	100%	2717.74	180 / 180	98%	32.04	420 / 430
bladder	100%	4402.43	21 / 21	97%	56.25	491 / 504
uterus	100%	3911.05	170 / 170	96%	46.53	440 / 459
skin	100%	5281.72	1809 / 1809	94%	58.64	446 / 472
kidney	99%	2097.57	88 / 89	95%	46.07	856 / 901
prostate	100%	3889.89	245 / 245	94%	40.36	471 / 502
adrenal gland	100%	2219.58	257 / 258	72%	14.26	165 / 230
liver	98%	1467.81	222 / 226	71%	18.77	289 / 406
brain	39%	458.81	1038 / 2642	95%	28.11	672 / 705
adipose	100%	5686.40	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4113.97	1335 / 1335	0%	0	0 / 0
spleen	100%	5318.10	241 / 241	0%	0	0 / 0
peripheral blood	99%	6181.06	916 / 929	0%	0	0 / 0
muscle	97%	1611.31	778 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	63.31	28 / 29
heart	96%	2120.20	828 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	53.54	43 / 45
eye	0%	0	0 / 0	80%	25.69	64 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0030154	Biological process	cell differentiation
GO_0001817	Biological process	regulation of cytokine production
GO_0050860	Biological process	negative regulation of T cell receptor signaling pathway
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0005515	Molecular function	protein binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]

Gene name	ELF1
Protein name	Alternative protein ELF1 ETS-related transcription factor Elf-1 (E74-like factor 1) E74 like ETS transcription factor 1
Synonyms
Description	FUNCTION: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. .
Accessions	P32519 ENST00000239882.7 [P32519-1] L8E9U9 A0A0U1RRL5 ENST00000625359.1 [P32519-2] Q5T9E7 ENST00000498824.4 ENST00000405737.2 ENST00000635415.1 A0A0D9SG85

ELF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review