Insufficient scRNA-seq data for expression of ACSBG2 at single-cell level.
Insufficient scRNA-seq data for expression of ACSBG2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 94% | 15.24 | 170 / 180 | 3% | 0.04 | 14 / 430 |
| kidney | 94% | 43.56 | 84 / 89 | 2% | 0.03 | 15 / 901 |
| uterus | 94% | 21.69 | 160 / 170 | 0% | 0.01 | 2 / 459 |
| prostate | 93% | 37.16 | 229 / 245 | 0% | 0.00 | 1 / 502 |
| breast | 88% | 36.53 | 404 / 459 | 2% | 0.04 | 24 / 1118 |
| brain | 85% | 23.31 | 2257 / 2642 | 4% | 0.06 | 27 / 705 |
| esophagus | 87% | 54.03 | 1252 / 1445 | 1% | 0.02 | 2 / 183 |
| bladder | 86% | 8.86 | 18 / 21 | 0% | 0.01 | 2 / 504 |
| intestine | 85% | 16.98 | 822 / 966 | 0% | 0.00 | 1 / 527 |
| spleen | 84% | 10.28 | 202 / 241 | 0% | 0 | 0 / 0 |
| thymus | 83% | 15.61 | 545 / 653 | 0% | 0 | 0 / 605 |
| lung | 81% | 13.40 | 467 / 578 | 2% | 0.03 | 20 / 1155 |
| skin | 77% | 11.63 | 1399 / 1809 | 0% | 0.00 | 1 / 472 |
| adipose | 77% | 15.62 | 931 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 77% | 14.07 | 1024 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 73% | 7.87 | 239 / 328 | 1% | 0.04 | 2 / 178 |
| stomach | 71% | 9.61 | 254 / 359 | 2% | 0.03 | 5 / 286 |
| adrenal gland | 59% | 5.88 | 153 / 258 | 0% | 0 | 0 / 230 |
| liver | 48% | 4.84 | 108 / 226 | 0% | 0 | 0 / 406 |
| heart | 35% | 3.12 | 303 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 31% | 5.42 | 287 / 929 | 0% | 0 | 0 / 0 |
| muscle | 18% | 5.44 | 146 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042759 | Biological process | long-chain fatty acid biosynthetic process |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0030154 | Biological process | cell differentiation |
| GO_0006631 | Biological process | fatty acid metabolic process |
| GO_0035338 | Biological process | long-chain fatty-acyl-CoA biosynthetic process |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0047617 | Molecular function | fatty acyl-CoA hydrolase activity |
| GO_0004467 | Molecular function | long-chain fatty acid-CoA ligase activity |
| GO_0047676 | Molecular function | arachidonate-CoA ligase activity |
| GO_0031957 | Molecular function | very long-chain fatty acid-CoA ligase activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | ACSBG2 |
| Protein name | long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) Acyl-CoA synthetase bubblegum family member 2 Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.15) (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2) (Arachidonate--CoA ligase ACSBG2) Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2) (Arachidonate--CoA ligase ACSBG2) Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2) (Arachidonate--CoA ligase ACSBG2) (EC 6.2.1.15) (Bubblegum-related protein) (PRTD-NY3) |
| Synonyms | UNQ2443/PRO5005 BGR |
| Description | FUNCTION: Catalyzes the conversion of fatty acids such as long chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids . Has increased ability to activate oleic and linoleic acid . May play a role in spermatogenesis . . |
| Accessions | K7ESF1 ENST00000589401.5 ENST00000681525.1 A0A7P0Z4L8 K7ERT0 K7EMB4 ENST00000588485.6 [Q5FVE4-1] ENST00000586696.5 [Q5FVE4-1] ENST00000591403.5 [Q5FVE4-1] K7EKE4 ENST00000587617.1 ENST00000588304.5 [Q5FVE4-2] ENST00000588722.5 K7EL11 ENST00000592677.5 ENST00000681479.1 ENST00000590132.1 Q5FVE4 K7ESC8 ENST00000587227.1 ENST00000591738.5 |