Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 8 studies | 26% ± 7% | |
epithelial cell | 7 studies | 31% ± 15% | |
astrocyte | 6 studies | 26% ± 9% | |
plasmacytoid dendritic cell | 6 studies | 25% ± 8% | |
glutamatergic neuron | 5 studies | 34% ± 21% | |
fibroblast | 5 studies | 23% ± 8% | |
natural killer cell | 5 studies | 20% ± 5% | |
abnormal cell | 5 studies | 22% ± 3% | |
pancreatic A cell | 4 studies | 31% ± 6% | |
myeloid cell | 4 studies | 19% ± 4% | |
ciliated cell | 4 studies | 23% ± 6% | |
macrophage | 4 studies | 23% ± 3% | |
oligodendrocyte precursor cell | 4 studies | 26% ± 9% | |
dendritic cell | 4 studies | 28% ± 10% | |
basal cell | 4 studies | 26% ± 9% | |
non-classical monocyte | 3 studies | 27% ± 9% | |
neuron | 3 studies | 32% ± 5% | |
pericyte | 3 studies | 18% ± 2% | |
GABAergic neuron | 3 studies | 39% ± 14% | |
goblet cell | 3 studies | 20% ± 3% | |
oligodendrocyte | 3 studies | 20% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 9253.58 | 2642 / 2642 | 100% | 129.79 | 705 / 705 |
esophagus | 100% | 6168.83 | 1445 / 1445 | 100% | 115.15 | 183 / 183 |
liver | 100% | 5461.20 | 226 / 226 | 100% | 109.01 | 406 / 406 |
ovary | 100% | 6601.26 | 180 / 180 | 100% | 126.59 | 430 / 430 |
pancreas | 100% | 4244.02 | 328 / 328 | 100% | 89.57 | 178 / 178 |
skin | 100% | 8300.00 | 1809 / 1809 | 100% | 158.76 | 472 / 472 |
uterus | 100% | 6273.04 | 170 / 170 | 100% | 101.84 | 459 / 459 |
thymus | 100% | 7099.25 | 653 / 653 | 100% | 102.64 | 604 / 605 |
intestine | 100% | 6395.29 | 966 / 966 | 100% | 93.68 | 525 / 527 |
prostate | 100% | 6064.85 | 245 / 245 | 100% | 120.31 | 500 / 502 |
kidney | 100% | 6951.24 | 89 / 89 | 100% | 90.45 | 897 / 901 |
stomach | 100% | 6042.18 | 359 / 359 | 99% | 107.19 | 284 / 286 |
breast | 100% | 6828.16 | 459 / 459 | 99% | 112.89 | 1109 / 1118 |
adrenal gland | 100% | 14494.57 | 258 / 258 | 99% | 119.87 | 228 / 230 |
lung | 100% | 6029.65 | 578 / 578 | 99% | 98.54 | 1143 / 1155 |
bladder | 100% | 5955.57 | 21 / 21 | 99% | 105.22 | 497 / 504 |
adipose | 100% | 6929.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 165.50 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 92.24 | 29 / 29 |
muscle | 100% | 7102.56 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5904.13 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 103.66 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 66.38 | 1 / 1 |
blood vessel | 100% | 6150.64 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 5777.18 | 848 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 3893.36 | 903 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0033081 | Biological process | regulation of T cell differentiation in thymus |
GO_0030154 | Biological process | cell differentiation |
GO_0012505 | Cellular component | endomembrane system |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0050811 | Molecular function | GABA receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CLPTM1 |
Protein name | Cleft lip and palate associated transmembrane protein 1 isoform 1 Cleft lip and palate associated transmembrane protein 1 isoform 2 (Cleft lip and palate associated transmembrane protein 1, isoform CRA_b) Putative lipid scramblase CLPTM1 (Cleft lip and palate transmembrane protein 1) CLPTM1 regulator of GABA type A receptor forward trafficking |
Synonyms | hCG_20220 |
Description | FUNCTION: Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate (By similarity). Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one (By similarity). Required for efficient glycosylphosphatidylinositol (GPI) inositol deacylation in the ER, which is a crucial step to switch GPI-anchored proteins (GPI-APs) from protein folding to transport states . May play a role in T-cell development (By similarity). . |
Accessions | ENST00000585961.1 ENST00000541297.6 [O96005-4] K7EKQ7 A0A0S2Z3H6 K7EQQ1 ENST00000589347.1 K7EJ16 K7ERL5 A0A0S2Z3H2 ENST00000586915.1 ENST00000591304.1 ENST00000337392.10 [O96005-1] O96005 ENST00000546079.5 [O96005-3] |