I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| brush cell | 4 studies | 27% ± 6% | |
| enterocyte | 4 studies | 22% ± 3% | |
| goblet cell | 3 studies | 19% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brush cell | 4 studies | 27% ± 6% | |
| enterocyte | 4 studies | 22% ± 3% | |
| goblet cell | 3 studies | 19% ± 3% |
Insufficient scRNA-seq data for expression of MYO7B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 7632.06 | 965 / 966 | 92% | 47.81 | 486 / 527 |
| kidney | 100% | 2781.81 | 89 / 89 | 68% | 11.13 | 617 / 901 |
| stomach | 56% | 199.62 | 201 / 359 | 81% | 36.79 | 232 / 286 |
| bladder | 90% | 280.00 | 19 / 21 | 27% | 11.31 | 138 / 504 |
| lung | 100% | 1106.21 | 576 / 578 | 14% | 4.01 | 167 / 1155 |
| esophagus | 66% | 245.24 | 948 / 1445 | 46% | 21.77 | 84 / 183 |
| thymus | 90% | 420.77 | 590 / 653 | 10% | 1.51 | 63 / 605 |
| spleen | 100% | 5928.98 | 241 / 241 | 0% | 0 | 0 / 0 |
| pancreas | 26% | 69.94 | 86 / 328 | 72% | 16.83 | 129 / 178 |
| heart | 97% | 608.39 | 834 / 861 | 0% | 0 | 0 / 0 |
| uterus | 85% | 349.92 | 144 / 170 | 12% | 2.86 | 54 / 459 |
| peripheral blood | 95% | 1009.33 | 884 / 929 | 0% | 0 | 0 / 0 |
| adipose | 92% | 484.64 | 1104 / 1204 | 0% | 0 | 0 / 0 |
| breast | 88% | 436.44 | 405 / 459 | 1% | 0.07 | 11 / 1118 |
| prostate | 80% | 299.23 | 196 / 245 | 1% | 0.03 | 3 / 502 |
| blood vessel | 80% | 252.75 | 1070 / 1335 | 0% | 0 | 0 / 0 |
| skin | 64% | 208.08 | 1153 / 1809 | 5% | 0.82 | 25 / 472 |
| muscle | 50% | 103.50 | 402 / 803 | 0% | 0 | 0 / 0 |
| liver | 27% | 71.06 | 60 / 226 | 21% | 1.99 | 84 / 406 |
| brain | 32% | 64.82 | 833 / 2642 | 11% | 0.85 | 77 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 34% | 1.80 | 10 / 29 |
| ovary | 21% | 46.28 | 37 / 180 | 11% | 0.94 | 48 / 430 |
| adrenal gland | 28% | 55.01 | 73 / 258 | 3% | 0.23 | 6 / 230 |
| eye | 0% | 0 | 0 / 0 | 18% | 5.01 | 14 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 0.31 | 2 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007015 | Biological process | actin filament organization |
| GO_0007605 | Biological process | sensory perception of sound |
| GO_1904970 | Biological process | brush border assembly |
| GO_0006897 | Biological process | endocytosis |
| GO_0030154 | Biological process | cell differentiation |
| GO_0007423 | Biological process | sensory organ development |
| GO_0030048 | Biological process | actin filament-based movement |
| GO_0005903 | Cellular component | brush border |
| GO_0005902 | Cellular component | microvillus |
| GO_0015629 | Cellular component | actin cytoskeleton |
| GO_0090651 | Cellular component | apical cytoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0016459 | Cellular component | myosin complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0000146 | Molecular function | microfilament motor activity |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | MYO7B |
| Protein name | Unconventional myosin-VIIb Myosin VIIB |
| Synonyms | |
| Description | FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length . May link the complex to the actin core bundle of microvilli. . |
| Accessions | ENST00000428314.5 [Q6PIF6-1] ENST00000409816.8 A0A8C8KL71 ENST00000409090.1 B9A063 ENST00000437387.5 Q6PIF6 C9JC21 |
