CNMD | OmnibusX

Name	Number of supported studies	Average coverage
Mueller cell	3 studies	21% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CNMD at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	97%	144.45	2553 / 2642	50%	3.35	354 / 705
thymus	78%	59.75	512 / 653	45%	13.86	271 / 605
prostate	29%	10.60	71 / 245	31%	1.26	155 / 502
pancreas	14%	3.00	45 / 328	23%	0.73	41 / 178
spleen	23%	4.49	56 / 241	0%	0	0 / 0
lung	6%	3.27	32 / 578	16%	19.26	190 / 1155
esophagus	11%	3.68	152 / 1445	5%	0.16	10 / 183
ovary	2%	0.70	3 / 180	9%	0.75	37 / 430
adrenal gland	1%	0.33	2 / 258	7%	0.55	17 / 230
stomach	1%	0.10	2 / 359	7%	0.34	21 / 286
uterus	1%	0.10	1 / 170	7%	0.99	32 / 459
eye	0%	0	0 / 0	8%	0.27	6 / 80
intestine	4%	1.00	34 / 966	3%	0.08	15 / 527
breast	2%	0.58	11 / 459	2%	1.88	26 / 1118
kidney	0%	0	0 / 89	4%	3.45	40 / 901
bladder	0%	0	0 / 21	4%	2.14	19 / 504
skin	1%	0.30	11 / 1809	3%	0.11	13 / 472
tonsil	0%	0	0 / 0	2%	1.05	1 / 45
peripheral blood	2%	0.56	18 / 929	0%	0	0 / 0
heart	1%	0.11	5 / 861	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0.05	2 / 406
adipose	0%	0.09	4 / 1204	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
blood vessel	0%	0	0 / 1335	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001501	Biological process	skeletal system development
GO_0001937	Biological process	negative regulation of endothelial cell proliferation
GO_0006029	Biological process	proteoglycan metabolic process
GO_0030154	Biological process	cell differentiation
GO_0051216	Biological process	cartilage development
GO_0016525	Biological process	negative regulation of angiogenesis
GO_0012505	Cellular component	endomembrane system
GO_0005576	Cellular component	extracellular region
GO_0016020	Cellular component	membrane

Gene name	CNMD
Protein name	Leukocyte cell-derived chemotaxin 1 (Chondromodulin) Leukocyte cell-derived chemotaxin 1 (Chondromodulin) [Cleaved into: Chondrosurfactant protein (CH-SP); Chondromodulin-1 (Chondromodulin-I) (ChM-I)]
Synonyms	LECT1 MYETS1 CHMI
Description	FUNCTION: Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization. .
Accessions	E9PKI9 ENST00000377962.8 [O75829-1] ENST00000448904.6 [O75829-2] ENST00000431550.1 O75829

CNMD report