I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 4 studies | 17% ± 1% | |
| GABAergic neuron | 3 studies | 17% ± 1% | |
| astrocyte | 3 studies | 19% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 4 studies | 17% ± 1% | |
| GABAergic neuron | 3 studies | 17% ± 1% | |
| astrocyte | 3 studies | 19% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 651.26 | 245 / 245 | 100% | 7.33 | 501 / 502 |
| thymus | 100% | 723.59 | 652 / 653 | 100% | 10.55 | 604 / 605 |
| brain | 100% | 579.09 | 2639 / 2642 | 100% | 11.92 | 703 / 705 |
| breast | 100% | 556.16 | 458 / 459 | 98% | 7.24 | 1092 / 1118 |
| kidney | 99% | 338.04 | 88 / 89 | 97% | 6.03 | 876 / 901 |
| uterus | 100% | 558.96 | 170 / 170 | 93% | 8.83 | 428 / 459 |
| pancreas | 96% | 213.05 | 316 / 328 | 94% | 5.28 | 168 / 178 |
| skin | 98% | 420.32 | 1765 / 1809 | 92% | 6.53 | 432 / 472 |
| lung | 99% | 395.28 | 574 / 578 | 85% | 4.97 | 985 / 1155 |
| ovary | 100% | 700.20 | 180 / 180 | 84% | 4.13 | 363 / 430 |
| adrenal gland | 100% | 384.84 | 257 / 258 | 83% | 3.33 | 190 / 230 |
| bladder | 100% | 656.43 | 21 / 21 | 79% | 4.62 | 397 / 504 |
| liver | 100% | 352.81 | 225 / 226 | 79% | 3.88 | 320 / 406 |
| intestine | 100% | 448.64 | 965 / 966 | 59% | 2.43 | 310 / 527 |
| esophagus | 99% | 397.55 | 1426 / 1445 | 58% | 2.80 | 106 / 183 |
| stomach | 98% | 293.39 | 353 / 359 | 56% | 2.25 | 161 / 286 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 9.09 | 29 / 29 |
| spleen | 100% | 627.62 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.87 | 1 / 1 |
| adipose | 100% | 513.25 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 362.72 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 98% | 297.08 | 786 / 803 | 0% | 0 | 0 / 0 |
| heart | 96% | 307.65 | 829 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 10.02 | 43 / 45 |
| eye | 0% | 0 | 0 / 0 | 95% | 6.22 | 76 / 80 |
| peripheral blood | 93% | 259.42 | 863 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0007127 | Biological process | meiosis I |
| GO_0030154 | Biological process | cell differentiation |
| GO_0045911 | Biological process | positive regulation of DNA recombination |
| GO_2000781 | Biological process | positive regulation of double-strand break repair |
| GO_0007129 | Biological process | homologous chromosome pairing at meiosis |
| GO_0005694 | Cellular component | chromosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0035064 | Molecular function | methylated histone binding |
| GO_0008327 | Molecular function | methyl-CpG binding |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | ZCWPW1 |
| Protein name | Zinc finger CW type with PWWP domain 1 isoform 2 Zinc finger CW type with PWWP domain 1 isoform 1 Zinc finger CW-type PWWP domain protein 1 Zinc finger CW type with PWWP domain 1 isoform 3 Zinc finger CW-type and PWWP domain containing 1 Zinc finger CW type with PWWP domain 1 isoform 6 Zinc finger CW type with PWWP domain 1 isoform 4 Zinc finger CW-type and PWWP domain containing 1 (Zinc finger, CW type with PWWP domain 1, isoform CRA_a) Zinc finger CW type with PWWP domain 1 isoform 5 |
| Synonyms | hCG_32539 |
| Description | FUNCTION: Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3) . Facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs) (By similarity). Essential for male fertility and spermatogenesis (By similarity). Required for meiosis prophase I progression in male but not in female germ cells (By similarity). . |
| Accessions | A0A0S2Z5N7 ENST00000684423.1 ENST00000398027.6 [Q9H0M4-1] ENST00000490721.5 [Q9H0M4-4] ENST00000472716.1 H7C4V9 ENST00000360951.8 [Q9H0M4-5] A0A0S2Z6A9 A0A0S2Z5J5 A0A0S2Z5K5 A0A0S2Z602 A0A0S2Z5E1 Q9H0M4 A0A804HK41 C9JUV7 ENST00000471336.1 |
