Insufficient scRNA-seq data for expression of TLL2 at single-cell level.
Insufficient scRNA-seq data for expression of TLL2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 94% | 314.58 | 2481 / 2642 | 37% | 0.86 | 260 / 705 |
| prostate | 60% | 46.85 | 146 / 245 | 53% | 1.08 | 266 / 502 |
| stomach | 88% | 78.48 | 317 / 359 | 22% | 0.42 | 63 / 286 |
| thymus | 83% | 79.78 | 542 / 653 | 19% | 0.60 | 117 / 605 |
| heart | 97% | 465.31 | 834 / 861 | 0% | 0 | 0 / 0 |
| intestine | 82% | 75.73 | 793 / 966 | 14% | 0.35 | 73 / 527 |
| pancreas | 61% | 38.80 | 200 / 328 | 33% | 0.76 | 59 / 178 |
| spleen | 83% | 63.85 | 201 / 241 | 0% | 0 | 0 / 0 |
| uterus | 51% | 47.18 | 87 / 170 | 31% | 1.28 | 140 / 459 |
| ovary | 68% | 57.36 | 122 / 180 | 6% | 0.15 | 26 / 430 |
| esophagus | 46% | 71.38 | 671 / 1445 | 17% | 0.45 | 32 / 183 |
| kidney | 45% | 38.34 | 40 / 89 | 13% | 0.35 | 113 / 901 |
| muscle | 57% | 66.12 | 457 / 803 | 0% | 0 | 0 / 0 |
| adrenal gland | 2% | 3.59 | 6 / 258 | 37% | 2.13 | 85 / 230 |
| breast | 19% | 13.01 | 89 / 459 | 14% | 0.24 | 160 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 0.99 | 11 / 45 |
| bladder | 10% | 3.90 | 2 / 21 | 14% | 0.57 | 71 / 504 |
| skin | 18% | 9.58 | 317 / 1809 | 4% | 0.09 | 17 / 472 |
| lung | 3% | 1.44 | 16 / 578 | 17% | 0.56 | 201 / 1155 |
| adipose | 12% | 7.61 | 143 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 10% | 6.63 | 93 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 9% | 7.73 | 119 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.10 | 2 / 29 |
| liver | 4% | 1.84 | 8 / 226 | 2% | 0.11 | 8 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0048632 | Biological process | negative regulation of skeletal muscle tissue growth |
| GO_0030199 | Biological process | collagen fibril organization |
| GO_0016485 | Biological process | protein processing |
| GO_0030154 | Biological process | cell differentiation |
| GO_0009953 | Biological process | dorsal/ventral pattern formation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0004222 | Molecular function | metalloendopeptidase activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | TLL2 |
| Protein name | Tolloid-like protein 2 (EC 3.4.24.-) |
| Synonyms | KIAA0932 |
| Description | FUNCTION: Protease which specifically processes pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis. |
| Accessions | Q9Y6L7 ENST00000357947.4 |