ADIRF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030154Biological processcell differentiation
GO_0045600Biological processpositive regulation of fat cell differentiation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameADIRF
Protein nameAdipogenesis regulatory factor (Adipogenesis factor rich in obesity) (Adipose most abundant gene transcript 2 protein) (Adipose-specific protein 2) (apM-2)
Adipogenesis regulatory factor
SynonymsC10orf116
APM2
AFRO
DescriptionFUNCTION: Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin. .

AccessionsQ15847
ENST00000561504.1
Q5TBU2
ENST00000416348.1
ENST00000372013.8